Pharmacokinetics

Question 1

What is the formula of T1/2?

Answer 1

0.693* VD/CL

Question 2

What is dose/ drug concentration ?

Answer 2

VD

Question 3

What is the formula of bioavailability ?

Answer 3

Oral dose/IV DOSE

Question 4

What is the formula for VD in related to salt and bioavailability ?

Answer 4

VD= DOSECFSALT/Conc at time 0

Question 5

WHAT IS THE STEADY STATE CLEARED FORMULA IN RELATED TO RATE OF ABSORPTION ?

Answer 5

Css = RA/CL

Question 6

What is the enlarged formal of Css?

Answer 6

Dose* FS/CLt

Question 7

What is the formula of maintenance dose ?

Answer 7

Md = CssClT

Question 8

What is the formula of Initial dose ?

Answer 8

Css* tcl/FS

Question 9

What is the formula of loading dose.?

Answer 9

VdC/FS

Question 10

What is bio equivalent drugs.?

Answer 10

Two drugs with equal bioavailability and plasma concentration

Question 11

Is phenobarbital a cytochrome inducer?

Answer 11

Yes
Increases Phase 1 Metabolism

Question 12

Which drugs can easily get absorbed and difficult to excrete ?

Answer 12

Lipophillic

Question 13

What drugs should be given to pregnant women ?

Answer 13

High Mol weight and less lipophillic drugs