Acid Base Bioenergetics And Enzymology Flashcards

1
Q

What is the equation of henery hasselbach..?

A

pH= pka + log (A-)/HA

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2
Q

How do you differentiate between alkalosis and acidosis?

A

RESPIRATORY acidosis (less pH, High co2)
Metabolism acidosis (less ph, less HC03)
Respiratory alkalosis (high pH, less C02)
Metabolic alkalosis (high pH, high Hco3)

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3
Q

What is Michael Menen equation.?

A

When Vi is half of Vmax

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4
Q

When is Vi proportional to S in Michael Menten equation ?

A

When S is more than Km

Vi = Vmax(S)/Km

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5
Q

Do competitive inhibitors cross and non competitive inhibitor do not cross

A

Yes

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6
Q

Which inhibition causes decrease in Vmax and Km

A

Uncompetitive

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7
Q

Which inhibition causes increas in Km but not Vmax

A

Competitive

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8
Q

Which inhibition causes decrease in Vmax but nothing else ?

A

Noncompetitive

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9
Q

When delta G is negative and positive what is the reaction.?

A

Spontaneous and exergonic (negative)
Non spontaneous (positive)

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10
Q

What are the disorders of Metabolic acidosis ?

A

Diabetes mellitus
Lactic acidosis

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11
Q

Disorder of Respiratory acidosis ?

A

COPD
Asthma

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12
Q

Disorders of Metabolic alkalosis ?

A

Vomiting loss of H ions

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13
Q

Disorders of Respiratory alkalosis ?

A

Hyperventilation (anxiety, fever)
Aspirin Poisoning

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