Acid Base Bioenergetics And Enzymology Flashcards
What is the equation of henery hasselbach..?
pH= pka + log (A-)/HA
How do you differentiate between alkalosis and acidosis?
RESPIRATORY acidosis (less pH, High co2)
Metabolism acidosis (less ph, less HC03)
Respiratory alkalosis (high pH, less C02)
Metabolic alkalosis (high pH, high Hco3)
What is Michael Menen equation.?
When Vi is half of Vmax
When is Vi proportional to S in Michael Menten equation ?
When S is more than Km
Vi = Vmax(S)/Km
Do competitive inhibitors cross and non competitive inhibitor do not cross
Yes
Which inhibition causes decrease in Vmax and Km
Uncompetitive
Which inhibition causes increas in Km but not Vmax
Competitive
Which inhibition causes decrease in Vmax but nothing else ?
Noncompetitive
When delta G is negative and positive what is the reaction.?
Spontaneous and exergonic (negative)
Non spontaneous (positive)
What are the disorders of Metabolic acidosis ?
Diabetes mellitus
Lactic acidosis
Disorder of Respiratory acidosis ?
COPD
Asthma
Disorders of Metabolic alkalosis ?
Vomiting loss of H ions
Disorders of Respiratory alkalosis ?
Hyperventilation (anxiety, fever)
Aspirin Poisoning