DIGESTION AND ABSORPTION OF CARBOHYDRATES Flashcards

1
Q

SALIVARY AMYLASE BREAKS WHAT BOND AND WHAT ARE THE PRODUCTS ?

A

1,4 Glycosidic bonds.
The products are Maltose, Maltotriose, alpha limit dextrins

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2
Q

What are the brush border enzymes ?

A

Lactase
Maltase
Sucrase + isomaltase

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3
Q

What enzyme breaks alpha limit dextrins ?

A

Isomaltase

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4
Q

How is Fructose absorbed in the Small intestine ?

A

By Glut 5 transported

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5
Q

How is glucose and galactose absorbed in the small intestine ?

A

By active transport with Na+ diffusion and SGLT transport

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6
Q

How is glucose, Galactose and fructose transported to the liver ?

A

By Glut 2 transport

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7
Q

What is Glucose and galactose malabsorption ?

A

Caused by mutation of SLCA51 causing a defective SGLT-1
Fatal in early infants.
Diarrhoea and dehtdration

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8
Q

What is De vivo disease ?

A

Caused by mutation in SLCA21 causing. A defective GLUT 1 transported to the brain
AD
Infantile encephalopathy
Low glucose and Lactate in csf

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9
Q

What is fanconi Bickel syndrome ?

A

Defective GLUT-2 transporter
Glucose cannot exit live
Glycogen acumulation’

Failure to thrive
Hepatosplenomegaly
VITAMIN D RICKETS

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