Gluconeogenesis

Question 1

What are the steps of gluconeogenesis ?

Answer 1

Pyruvate (PYRUVATE CARBOXYLASE)
Oxaloacetate
Malate
Oxaloacetate (PEP CARBOXYKINASE)
Phosphoenol pyruvate
Fructose 1,6 Biphosphate (F1 BPase)
Fructose 6 Biphosphate
Glucose 6 Phosphate
Glucose

Question 2

What are the initial activator of Pyruvate CARBOXYLASE?

Answer 2

Acteyl CoA
ATP
Biotin

Question 3

What are the activators of Fructose 1,6 Biphosphatease?

Answer 3

Citrate
AMP
FRUCTOSE 2,6 BISPHOSPAHTESE

Question 4

What are the substrates for gluconeogenesis ?

Answer 4

Lactate
Alanine
Glycerol

Question 5

What is the rate limiting enzyme in gluconeogenesis ?

Answer 5

Fructose 1,6 Biphosphate to fructose 6 Phosphate (F16BPASE)

Question 6

What is the bifunctional enzymes that Activates gluconeogenesis and inhibits glycolysis.?

Answer 6

Fructose 2,6BPAse ( active in gluconeogenesis)

Phosphofrucktokinase 2 (active in glycolysis)

Question 7

What does Phosphofrucktokinase 2 produce ?

Answer 7

Pfk 2 —-> fructose 2,6 BP—> pfk1

PFK 1 is the rate limiting enzyme in glycolysis