Pustular Disorders Flashcards

1
Q

Acne Vulgaris

pathophys

4 components

A
  1. follicular hyperkeratinization
  2. increased sebum production
  3. Cutibacterium acnes overgrowth
  4. inflammatory response
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2
Q

Acne Vulgaris

dx

A

clinical

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3
Q

Acne Vulgaris

inflammatory skin condition associated w/

A
  • papules & pustules
  • which involve the pilosebaceous unit
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4
Q

Acne Vulgaris

classifications

5

A
  1. comedonal (open & closed)
  2. mild mixed acne
  3. moderate
  4. severe
  5. acne scars/hyperpigmentation
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5
Q

Acne Vulgaris

tx for comedonal

& advise pts?

A
  • topical retinoid
  • must treat whole face, NOT SPOT tx
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6
Q

Acne Vulgaris

how long until comedonal acne improves w/ tx?

A

4-6 wks

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7
Q

Acne Vulgaris

tx for mild mixed acne

2 components

A
  • topical retinoid
  • topical antimicrobial (clindamycin gel)
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8
Q

Acne Vulgaris

moderate tx

3 components

A

topical retinoid
topical antimicrobial
oral abx

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9
Q

Acne Vulgaris

severe tx

A

isotretinoin

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10
Q

Acne Vulgaris

most effective med for acne

A

isotretinoin (acutane)

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11
Q

Acne Vulgaris

PPP for isotretinoin

A
  • teratogenic
  • increased triglycerides
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12
Q

Acne Vulgaris

acne scars/hyperpigmentation tx

4 components

A

trichloroacetic acid
microneedling
retinoids
topical hydroquinone

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13
Q

Rosacea

triggers

A
  • alcohol
  • changes in weather
  • spicy foods
  • sun exposure
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14
Q

Rosacea

clinical presentation

5 components

A
  • macular erythema
  • telangiectasia
  • possible papules or pustules
  • possible: rhinophyma
  • ocular sx
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15
Q

Rosacea

what is telangiectasia

A

small, widened blood vessels

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16
Q

Rosacea

what is rhinophyma

A

overgrowth of dermis and sebaceous glands on the nose

17
Q

Rosacea

what ocular sx are present

5

A
  1. ocular erythema
  2. tearing
  3. foreign body sensation
  4. burning
  5. itching
18
Q

Rosacea

most commonly affects who?

A
  • adults
  • lighter skinned individuals
19
Q

Rosacea

diagnosis

A

clinical

20
Q

Rosacea

tx

mild/moderate, severe, facial erythema, telangiectasia

A
  1. topical metronidazole + topical ivermectin + topical sulfacetamide
  2. oral abx (doxy) + topical agent
  3. topical brimonidine
  4. laser therapy
21
Q

Milia

generally describe

A

skin eruption due to keratin retention & sebaceous material in the pilosebaceous follicles w/in the dermis

22
Q

Milia

clinical manifestations

2 components (appearance/location)

A
  1. 1-3mm pearly white/yellow papules
  2. seen especially on cheeks, forehead, chin, nose
23
Q

Milia

tx

A

observation

24
Q

Milia

when/how to manually remove?

A
  • cosmetic preferences
  • w/ liquid nitrogen
25
Q

Folliculitis

infection/inflammation where?

A

hair follicle

26
Q

Folliculitis

most common bacteria?

A

S. aureus

27
Q

Folliculitis

what to suspect w/ recent hot tub use?

A

Pseudomonas aeruginosa

28
Q

Folliculitis

risk factors

3

A
  1. men
  2. prolonged abx use
  3. topical steroids
29
Q

Folliculitis

clinical manifestations

A
  • solitary or clusters of perifollicular papules/pustules
  • surrounding erythema on hair bearing skin
30
Q

Folliculitis

tx

first line- 3 meds

A
  • topical mupirocin
  • clindamycin + benzoyl peroxide
  • erythromycin
31
Q

Folliculitis

tx for severe

2

A

oral cephalexin or dicloxacillin

32
Q

Perioral Dermatitis

commonly seen in who?

A

women ages 20 to 45 y/o

33
Q

Perioral Dermatits

risk factors

2

A
  • topical corticosteroid use
  • fluoridated toothpaste
34
Q

Perioral Dermatits

clinical manifestations

A
  1. erythematous group papules or pustules
  2. can confluence into plaques w/ scales
  3. spares the vermillion border
  4. may affect periorbital or paranasal skin
35
Q

Perioral Dermatits

tx

first line- 3 options, 1 preventive measure

A
  • topical pimecrolimus, metronidazole, or erythromycin
  • elimination of topical corticosteroids or other irritants
36
Q

Perioral Dermatits

tx- PO & when to use

A

tetracyclines
* use if extensive or refractory