Misc Derm Disorders Flashcards

1
Q

Cherry Angioma

How does this benign lesion form?

A

abnormal mature capillary proliferation

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2
Q

Cherry Angioma

most commonly seen in who?

A

middle aged and older adults

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3
Q

Cherry Angioma

Clinical Presentation

A
  1. cherry red to purple papules
  2. flat topped or dome shaped
  3. seen most commonly on trunk
  4. friable (bleed profusely when traumatized)
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4
Q

Cherry Angioma

Dx & Tx

A
  1. clinical dx
  2. tx is observation
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5
Q

Cherry Angioma

what would you do if the pt wanted removal for cosmetic reasons?

2 things

A
  • electrocauterization
  • laser therapy
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6
Q

Pyogenic Granuloma

most common in who?

A

young children and adults

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7
Q

Pyogenic Granuloma

seen after what?

A
  1. hormone changes (pregnancy)
  2. initation of new meds
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8
Q

Pyogenic Granuloma

benign vascular ____ of the skin or mucous membranes

A

tumor

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9
Q

Pyogenic Granuloma

clinical presentation

A
  1. solitary
  2. glistening
  3. bright red
  4. friable
  5. rapidly grows
  6. nodule or papule
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10
Q

Pyogenic Granuloma

dx & tx

A
  1. biopsy
  2. excision w/ wound closure or curettage followed by electrocautery
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11
Q

Kaposi Sarcoma

vascular cancer associated with which virus?

not asking which population it usually is seen in…

A

herpes virus 8

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12
Q

Kaposi Sarcoma

most commonly seen in who?

A

HIV pts (immunosuppressed)

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13
Q

Kaposi Sarcoma

where is it usually seen on the body?

A
  1. lower extremities
  2. face
  3. oral mucosa
  4. genitalia
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14
Q

Kaposi Sarcoma

clinical manifestations

A
  1. painless
  2. non-puruitic
  3. pink/brown/erythemtous/violaceous
  4. macules, plaques, or nodules
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15
Q

Kaposi Sarcoma

dx and tx

A
  1. biopsy
  2. refer to oncology
  3. initiate ART
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16
Q

Stasis Dermatitis

inflammatory skin changes associated with?

A

chronic venous insufficiency

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17
Q

Stasis Dermatitis

clinical presentation

A
  • erythematous/brown/violaceous hyperpigmented
  • patches or plaques
  • eczematous features (scales, pruritis, weeping erosions, crusting)
  • leg edema, increased leg circumference, variscosities
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18
Q

Stasis Dermatitis

what is maintained despite leg edema?

A

pulse

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19
Q

Stasis Dermatitis

tx

A
  1. overall: undelrying venous insufficiency
  2. acute lesions: topical corticosteroids
  3. severe/refractory: oral prednisone
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20
Q

Stasis Dermatitis

general meausres for tx

A
  • leg elevation
  • compressions socks
  • exercise
  • gentle cleansing
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21
Q

Decubitus Ulcer

results from what?

A

vertical pressure

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22
Q

Decubitus Ulcer

risk factors

A
  1. elderly
  2. immobile
  3. incontinence
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23
Q

Decubitus Ulcer

commonly seen on what body areas?

A

bony prominences

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24
Q

Decubitus Ulcer

what does pressure in the ulcer impair for the rest of the area?

A
  1. nutrient and O2 delivery
  2. waste remove
25
# Decubitus Ulcer what does mositure cause?
skin maceration
26
# Decubitus Ulcer manifestation of stage 1
* superficial * non-blanchable * erythematous macule
27
# Decubitus Ulcer tx of stage 1
* preventive measures * wound protection
28
# Decubitus Ulcer manifestation of stage 2
* epidermal damage extending into dermis * resembles bulla or abrasion
29
# Decubitus Ulcer tx for stage 2
* maintain moist wound environment via hydrocolloids or hydrogels
30
# Decubitus Ulcer manifestations of stage 3
* full thickness loss of skin * may extend into subQ layer
31
# Decubitus Ulcer manifestations of stage 4
* deepest of the 4 stages * extends beyond the fascia & into the muscle/tendon/bone
32
# Decubitus Ulcer tx for stage 3 & 4 wounds
1. wound cleansing 2. moist wound environment 3. debridement of necrotic tissue 4. tx of wound infection as needed
33
# Pyoderma Gangrene auto-inflammatory process mediated by what?
neutrophils into the dermis
34
# Pyoderma Gangrene triggered by what?
* trauma * surgical debridement * attempts to graft an area
35
# Pyoderma Gangrene associated with what conditions? | 5
1. IBD 2. Rheumatoid arthritis 3. malignancies 4. hematologic conditions 5. arthritis
36
# Pyoderma Gangrene often misdiagnosed as what?
spider bite bedridement
37
# Pyoderma Gangrene clinical maifestations | 4 components
1. small pustules that break down & rapidly expand to form an ulcer w/ a violaceous border 2. satellite ulcerations 3. anywhere on body 4. painful
38
# Pyoderma Gangrene how urgent is this?
emergent!
39
# Pyoderma Gangrene Topical tx | 2
1. superpotent steroids 2. tacrolimus
40
# Pyoderma Gangrene systemic tx | 6 options
1. steroids 2. cyclosporine 3. tacrolimus 4. cellcept 5. thalidomide 6. TNF-inhibitors
41
# Drug Eruptions how to get the rxn to stop?
stop the med!
42
# Drug Eruptions what type of rxn are these most often?
hypersensitivity
43
# Drug Eruptions triggers | 5
1. antigen from foods 2. insect bites 3. environmental 4. exercise induced 5. infections
44
# Drug Eruptions Class 1 mechanism
IgE-mediated
45
# Drug Eruptions class 2 mechanism
cytotoxic, antibody mediated
46
# Drug Eruptions class 3 mechanism
immune antibody-antigen complex
47
# Drug Eruptions class 4 mechanism
delayed (cell mediated)
48
# Drug Eruptions non-immunologic mechanism
genetic incapability to detoxify drugs
49
# Drug Eruptions when does a morbilliform drug eruption occur?
* 5 to 14 d after initiation of new med
50
# Drug Eruptions what type of rxn causes a morbilliform drug eruption?
type 4 hypersensitivity
51
# Drug Eruptions which meds commonly cause morbilliform drug eruption? | 5
1. PCN 2. sulfas 3. NSAIDs 4. allopurinol 5. anti-convulsants
52
# Drug Eruptions clinical presentation | 4
1. erythematous macules or small papules after initiation of med 2. generalized distribution 3. coalesce to form plaques 4. mild systemic sx
53
# Drug Eruptions tx
1. stop offending med 2. oral antihistamines 3. short course corticosteroids PO, PRN
54
# Vitiligo chronic, depigmenting disorder of the skin where which cell types are lost?
melanocytes
55
# Vitiligo appears in who? when?
* all races * all genders * most commonly appears 20-25 y/o
56
# Vitiligo associated with what other disease states? | general statement, not specific diseasess
autoimmune
57
# Vitiligo clinical manifestations
1. complete loss of pigment in macules or patches of the skin 2. chalky/milky white coloration 3. can be pruritic 4. convex borders
58
# Vitiligo typically found in what areas of the skin?
* sun exposed * areas prone to repetitive trauma
59
# Vitiligo tx
* topical potent corticosteroids