Inflammatory Nodule Disorders Flashcards
Lipoma
most common?
type of skin problem
benign soft tissue neoplasm
Lipoma
benign, subQ tumors composed of?
enclosed by?
- mature adipocytes
- thin, fiberous capsule
Lipoma
clinical manifestations
- soft, painless, subQ nodules that are easily mobile
- most commonly found in trunk, neck, upper extremities
Lipoma
dx
clinical
Lipoma
when is biopsy indicated?
- pain
- rapidly enlarging
- firm
- restricts movement
Lipoma
tx
- observation
- excision for cosmetic or sx purposes
Epidermal Inclusion Cyst
general overview
- benign, encapsulated, subepidermal nodules filled w/ fibrous tissue & keratinous material
Epidermal Inclusion Cyst
most common in who?
- 30s, 40s
- males 2x more likely than females
Epidermal Inclusion Cyst
pathophys
results from plugging follicular orifices
Epidermal Inclusion Cyst
clinical presentation
3 components
- asx
- skin coloral dermal, freely mobile, compressible cyst
- clinically visible central punctum
Epidermal Inclusion Cyst
what happens to ruptured, infected cysts?
- fluctuate
- painful
- erythematous
- may have foul smelling discharge
Epidermal Inclusion Cyst
tx
non-infected vs infected
- no tx necessary (excision for cosmetic)
- incision & drainage
Furuncle & Carbuncle
define a furuncle
deep infection of the hair follicle
Furuncle & Carbuncle
define carbuncle
coalescence or interconnection of several furuncles into a single mass w/ purulent drainage from many follicles
Furuncle & Carbuncle
most common bacteria?
- S. aureus
- staph
Furuncle & Carbuncle
clinical manifestations
6 things
- erythematous
- tender
- indurated
- nodule
- fluctance
- (+/-) cellulitis
Furuncle & Carbuncle
tx
- incision & drainage
- abx: trimethoprim-sulfamethoxazole, doxy, clindamycin
Hidradenitis Suppurativa
general overview
painful, chronic, inflammatory suppurative condition involving the skin and subq tissue
Hidradenitis Suppurativa
risk factors
5
- obesity
- females
- smoking
- hx of acne
- family hx
Hidradenitis Suppurativa
pathophys
thought to be due to chronic infra-infundibular follicular hiar follicle obstruction, followed by secondary rupture of the sebofollicular junction, resulting in an inflammatory rxn
Hidradenitis Suppurativa
clinical presentation
- recurrent, painful, deep-seated inflammatory nodules & abscesses
- draining tracts
- fibrotic hypertrophic scars that most commonly affect intertriginous skin
Hidradenitis Suppurativa
dx
clinical
Hidradenitis Suppurativa
components of lifestyle modification for tx
- avoid high glycemic foods
- smoking cessation
- local skin care
- eliminate irritants
- wt loss
Hidradenitis Suppurativa
tx when only inflammatory lesions present
- topical clindamycin
- can have anti-angiogenic drugs or metformin
Hidradenitis Suppurativa
tx when inflammatory lesions w/ sinus tracks or scarring
- oral tetracycline (doxy)
or - clindamycin w/ rifampin
