Pulm Flashcards
V/Q Ratio of APEX at rest
3
V/Q Ratio of BASE at rest
0.6
V/Q Ratio of APEX at exercise
1 (vasodilation of apical capillaries)
V/Q Ratio of 0
SHUNT (airway obstructed, so 100% O2 will not help)
V/Q Ratio of infinity
PHYSIOLOGIC DEAD SPACE (blood flow obstruction, so 100% O2 will help)
Pressures at APEX
PA > Pa > Pv
Pressures at middle lung
Pa > PA > Pv
Pressures at BASE
Pa > Pv > PA
Where is CO2 bound on carbaminohemoglobin?
N-terminus of globin
What part of the lung does asbestosis affect?
lower lobes
What part of the lung do silica and coal affect?
upper lobes
What is anthracosis?
asymptomatic condition of urban dwellers exposed to sooty air
What does silicosis increase risk for?
- Tb (disrupts phagolysosomes and macrophages)
- Branchogenic carcinoma
Lung cancer that cavitates
squamous cell carcinoma
Lung cancer that is most common in non-smokers (and overall)
adenocarcinoma