Pharmacology Flashcards

1
Q

Antidote for Acetaminophen

A

N-acetylcysteine (replenish glutathione)

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2
Q

Antidote for AchE inhibitors (organophosphates)

A

Atropine (followed by pralidoxime)

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3
Q

Antidote for Amphetamines

A

NH4Cl (acidify urine)

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4
Q

Antidote for Antimuscarinic agents

A

Physostigmine salicylate

Control hyperthermia

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5
Q

Antidote for benzodiazepines

A

Flumazenil

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6
Q

Antidote for beta-blockers

A

Glucagon

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7
Q

Antidote for CO

A

100% O2 (or hyperbaric O2)

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8
Q

Antidote for copper, arsenic, gold

A

penicillamine

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9
Q

Antidote for cyanide

A

nitrite + thiosulfate

hydroxocobalamin

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10
Q

Antidote for digitalis

A

anti-dig Fab fragments

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11
Q

Antidote for heparin

A

Protamine sulfate

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12
Q

Antidote for iron

A

deferoxamine

deferasirox

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13
Q

Antidote for lead

A

EDTA
dimercaprol
succimer
penicillamine

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14
Q

Antidote for mercury, arsenic, gold

A

dimercaprol (BAL), succimer

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15
Q

Antidote for methanol or ethylene glycol

A

Fomepizole > ethanol; dialysis

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16
Q

Antidote for methemoglobin

A

Methylene blue

Vitamin C

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17
Q

Antidote for opioids

A

Naloxone

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18
Q

Antidote for salicylates

A

NaHCO3 (alkalinize urine)

Dialysis

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19
Q

Antidote for TCAs

A

NaHCO3 (plasma alkalinnization)

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20
Q

Antidote for tPA, streptokinase, urokinase

A

aminocaproic acid

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21
Q

Antidote for warfarin

A

Vitamin K

FFP (if bleeding)

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22
Q

Drugs that cause coronary vasospasm

A

Cocaine
Sumatriptan
Ergots

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23
Q

Drugs that cause cutaneous flushing

A

Vancomycin
Adenosine
Niacin
CCBs

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24
Q

Drugs that cause dilated cardiomyopathy

A

Doxorubicin

Daunorubicin

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25
Drugs that cause torsades de pointes
Class III (sotalol) and Class IA (quinidine) antiarrhythmics, macrolides, antipsychotics, and TCAs
26
Drugs that cause adrenocortical insufficiency
HPA suppression secondary to glucocorticoid withdrawal
27
Drugs that cause hot flashes
tamoxifen | clomiphene
28
Drugs that cause hyperglycemia
``` Tacrolimus Protease inhibitors Niacin HCTZ Beta-blockers Corticosteroid (Taking Pills Necessitiates Having Blood Checked) ```
29
Drugs that cause hyopthyroidism
LIthium Amiodarone Sulfonamides
30
Drugs that cause acute cholestatic hepatitis (jaundice)
erythromycin
31
Drugs that cause diarrhea
``` Metformin Erythromycin Colchicine Orlistat Acarbose (Might Excite Colon On ACcident) ```
32
Drugs that cause focal to massive hepatic necrosis
``` Halothane Amanita phalloides (death cap mushroom) Valproic acid Acetaminophen (Liver "HAVAc") ```
33
Drugs that cause heptitis
INH
34
Drugs that cause pancreatitis
``` Didanosine Corticosteroids Alcohol Valproic acid Azathioprine DIuretics (furosemide, HCTZ) (Drugs Causing A Violent Abdominal Distress) ```
35
Drugs that cause Pseudomembranous Colitis
Clindamycin Ampicillin Cephalosporins (all predispose to superinfeciton by C. diff)
36
Drugs that cause agranolocytosis
``` Dapsone Clozapine Carbamazepine Colchicine Methimaxole PTU (Drugs CCCrush Myeloblasts & Promyelocytes) ```
37
Drugs that cause aplastic anemia
``` Carbamazepine Methimaxole NSAIDs Benzene Chloramphenicol PTU (Can't Make New Blood Cells Properly) ```
38
Drugs that cause hemolytic anemia (direct coombs positive)
Methyldopa | Penicillin
39
Drugs that cause gray baby syndrome
Chloramphenicol
40
Drugs that cause hemolysis in G6PD deficiency
``` INH SUlfonamides Dapsone Primaquine Aspirin Ibuprofen Nitrofurantoin (Hemolysis IS D PAIN) ```
41
Drugs that cause megaloblastic anemia
Phenytoin Methotrexate Sulfas (Have a blast with PMS)
42
Drugs that cause thrombocytopenia
Heparin | Cimetidine
43
Drugs that cause thrombotic compications
OCPs (estrogens)
44
Drugs that cause fat redistribution
Proetase inhibitors Glucocorticoids (fat PiG)
45
Drugs that cause gingival hyperplasia
Phenytoin Verapamil Cyclosporine Nifedipine
46
Drugs that cause Hyperuricemia (gout)
``` Pyrazinamide Thiazides Furosemide Niacin Cyclosporine (Painful Tophi & Feet Need Care) ```
47
Drugs that cause myopathy
``` Fibrates Niacin Colchicine Hydoxychloroquine INF-alpha Penicillamine Statins Glucocorticoids ```
48
Drugs that cause osteoporosis
Corticosteroids | Heparin
49
Drugs that cause photosensitivity
``` Sulfonamides Amiodarone Tetracyclines 5-FU (SAT For Photo) ```
50
Drugs that cause SJS (rash)
Anti-epileptic drugs (ex. lamotrigine) Allopurinol Sulfa drugs Penicillin
51
Drugs that cause teeth discoloration
tetracyclines
52
Drugs that cause Tendonitis, tendon rupture and cartilage damage
fluoroquinolones
53
Drugs that cause SLE-like syndrome
``` Sulfa durgs Hydralazine INH Procainamide Phenytoin Etanercept ```
54
Drugs that cause cinchonism (flushed, sweaty, tinnitus, hearing loss, glurred vision)
quinidine | quinine
55
Drugs that cause Parkinson-like syndrome
Antipsychotics Reserpine Metoclopramide
56
Drugs that cause seizures
``` INH (vit B6 deficiency) Bupropion Imipenem/cilastatin Tramadol Enflurane Metoclopramide ```
57
Drugs that cause tardive dyskinesia
Antipsychotics | Metoclopramide
58
Drugs that cause diabetes insipidus
lithium | demeclocycline
59
Drugs that cause Fanconi syndrome
Expired tetracycline
60
Drugs that cause hemorrhage cystitis
Cyclophosphamide Ifosfamide (give with mesna to prevent)
61
Drugs that cause intestinal nephritis
Methicillin NSAIDs Furosemide
62
Drugs that cause SIADH
Carbamazepine Cyclophosphamide SSRIs
63
Drugs that cause dry cough
ACE inhibitors
64
Drugs that cause pulmonary fibrosis
``` Bleomycin Amiodarone Busulfan Methotrexate (Breathing Air Badly from Medications) ```
65
Drugs that cause disulfiram-like reaction
``` Metronidazole Certain cephalosporins Griseofulvin Procarbazine 1st generation sulfonylureas ```
66
Drugs that cause nephrotoxicity/ototoxicity
Aminoglycosides Vancomycin Loops Cisplatin
67
Sulfa drugs
``` Probenecid Furosemide Acetazolamide Celecoxib Thiazides Sulfonamide antibiotics Sulfasalazine Sulfonylureas ```
68
-azole
ergosterol synthesis inhibitor
69
-bendazole
antiparasitic/antihelmintic
70
-cillin
peptidoglycan synthesis inhibitor
71
-cycline
protein synthesis inhibitor
72
-ivir
neuraminidase inhibitor
73
-navir
Protease inhibitor
74
-ovir
DNA polymerase inhibitor
75
-thromycin
Macrolide
76
-ane
inhalational general anesthetic
77
-azine
typical antipsychotic
78
-barbital
barbiturate (duratuation)
79
-caine
local anesthetic
80
-etine
SSRI
81
-ipramine
TCA
82
-triptan
5-HT 1B/1D agonist
83
-tryptyline
TCA
84
-zepam
Benzo (frequency)
85
-zolam
Benzo (frequency)
86
-chol
cholinergic agonist
87
-curium or -curonium
non-depolarizing paralytic
88
-olol
beta blocker
89
-stigmine
AchE inhibitor
90
-terol
beta2 agonsit
91
-zosin
alpha1-antagonist
92
-afil
PDE-5 inhibitor
93
-dipine
Dihydropyridine CCB
94
-pril
ACE inhibitor
95
-sartan
Antiotensin-II receptor blocker
96
-statin
HMG-CoA reductase inhibitor
97
-dronate
bisphosphonate
98
-glitazone
PPAR-gamma activator
99
-prazole
PPI
100
-prost
Prostaglandin analog
101
-tidine
H2-antagonist
102
-tropin
Pituitary hormone
103
-ximab
Chimeric mAb
104
-zumab
humanized mAb