Pharmacology Flashcards
Antidote for Acetaminophen
N-acetylcysteine (replenish glutathione)
Antidote for AchE inhibitors (organophosphates)
Atropine (followed by pralidoxime)
Antidote for Amphetamines
NH4Cl (acidify urine)
Antidote for Antimuscarinic agents
Physostigmine salicylate
Control hyperthermia
Antidote for benzodiazepines
Flumazenil
Antidote for beta-blockers
Glucagon
Antidote for CO
100% O2 (or hyperbaric O2)
Antidote for copper, arsenic, gold
penicillamine
Antidote for cyanide
nitrite + thiosulfate
hydroxocobalamin
Antidote for digitalis
anti-dig Fab fragments
Antidote for heparin
Protamine sulfate
Antidote for iron
deferoxamine
deferasirox
Antidote for lead
EDTA
dimercaprol
succimer
penicillamine
Antidote for mercury, arsenic, gold
dimercaprol (BAL), succimer
Antidote for methanol or ethylene glycol
Fomepizole > ethanol; dialysis
Antidote for methemoglobin
Methylene blue
Vitamin C
Antidote for opioids
Naloxone
Antidote for salicylates
NaHCO3 (alkalinize urine)
Dialysis
Antidote for TCAs
NaHCO3 (plasma alkalinnization)
Antidote for tPA, streptokinase, urokinase
aminocaproic acid
Antidote for warfarin
Vitamin K
FFP (if bleeding)
Drugs that cause coronary vasospasm
Cocaine
Sumatriptan
Ergots
Drugs that cause cutaneous flushing
Vancomycin
Adenosine
Niacin
CCBs
Drugs that cause dilated cardiomyopathy
Doxorubicin
Daunorubicin
Drugs that cause torsades de pointes
Class III (sotalol) and Class IA (quinidine) antiarrhythmics, macrolides, antipsychotics, and TCAs
Drugs that cause adrenocortical insufficiency
HPA suppression secondary to glucocorticoid withdrawal
Drugs that cause hot flashes
tamoxifen
clomiphene
Drugs that cause hyperglycemia
Tacrolimus Protease inhibitors Niacin HCTZ Beta-blockers Corticosteroid (Taking Pills Necessitiates Having Blood Checked)
Drugs that cause hyopthyroidism
LIthium
Amiodarone
Sulfonamides
Drugs that cause acute cholestatic hepatitis (jaundice)
erythromycin
Drugs that cause diarrhea
Metformin Erythromycin Colchicine Orlistat Acarbose (Might Excite Colon On ACcident)
Drugs that cause focal to massive hepatic necrosis
Halothane Amanita phalloides (death cap mushroom) Valproic acid Acetaminophen (Liver "HAVAc")
Drugs that cause heptitis
INH
Drugs that cause pancreatitis
Didanosine Corticosteroids Alcohol Valproic acid Azathioprine DIuretics (furosemide, HCTZ) (Drugs Causing A Violent Abdominal Distress)
Drugs that cause Pseudomembranous Colitis
Clindamycin
Ampicillin
Cephalosporins
(all predispose to superinfeciton by C. diff)
Drugs that cause agranolocytosis
Dapsone Clozapine Carbamazepine Colchicine Methimaxole PTU (Drugs CCCrush Myeloblasts & Promyelocytes)
Drugs that cause aplastic anemia
Carbamazepine Methimaxole NSAIDs Benzene Chloramphenicol PTU (Can't Make New Blood Cells Properly)
Drugs that cause hemolytic anemia (direct coombs positive)
Methyldopa
Penicillin
Drugs that cause gray baby syndrome
Chloramphenicol
Drugs that cause hemolysis in G6PD deficiency
INH SUlfonamides Dapsone Primaquine Aspirin Ibuprofen Nitrofurantoin (Hemolysis IS D PAIN)
Drugs that cause megaloblastic anemia
Phenytoin
Methotrexate
Sulfas
(Have a blast with PMS)