Heme Flashcards

1
Q

Causes of microcytic (<80 fL= MCV) anemia

A
Iron deficiency (late)
ACD (late)
Thalassemias
Lead poisoning
Sideroblastic anemia
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2
Q

Causes of Non-Hemolytic, Normocytic (MCV= 80-100) anemia

A

ACD (early)
Aplastic anemia
Chronic Kidney Disease
Iron deficiency (early)

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3
Q

Causes of Intrinsic Hemolytic, Normocytic (MCV= 80-100) anemia

A
Hereditary spherocytosis
G6PD Deficiency
HbC
Paroxysmal nocturnal hemoglobinuria
Sickle cell anemia
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4
Q

Causes of Extrinsic Hemolytic, Normocytic (MCV= 80-100) anemia

A

Autoimmune
Microangiopathic
Macroangiopathic
Infections

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5
Q

Causes of Megaloblastic Macrocytic (MCV >100 fL) anemia

A

Folate deficiency
B12 deficiency
Orotic aciduria

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6
Q

Causes of Non-Megaloblastic Macrocytic (MCV >100 fL) anemia

A

Liver disease
Alcoholism
Reticulocytosis

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7
Q

t(9;22)

A

CML

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8
Q

t(8;14)

A

Burkitt lymphoma

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9
Q

t(11;14)

A

Mantle cell lymphoma

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10
Q

t(14;18)

A

Follicular lymphoma

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11
Q

t(15;17)

A

M3 type of AML

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12
Q

Bcr-abl

A

CML

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13
Q

Bcl-2

A

Follicular lymphoma

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14
Q

C-myc

A

Burkitt lymphoma

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15
Q

Cyclin D1

A

Mantle cell lymphoma

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16
Q

Lymphoma/leukemias that occur in young

A

Burkitt lymphoma
Diffuse Large-B cell lymphoma (20% in kids)
ALL

17
Q

Smudge cells

A

SLL/CLL

18
Q

Auer rods

A

AML (M3 type)

19
Q

low LAP

A

CML