puberty

Question 1

secretion of sex steroid hormones after regeneration fo the zona reticularis in the adrenal cortex is?

Answer 1

adrenarche

Question 2

when does adrenarche occur?

Answer 2

age 6-8

Question 3

when does gonadarche begin?

Answer 3

age 8

Question 4

pulsatile gnRH is incr without phenotypic changes is what stage?

Answer 4

gonadarche

Question 5

when breast bud development begins

Answer 5

thelarche

Question 6

thelarche begins when

Answer 6

11

Question 7

breast buds are generated in response to _____

Answer 7

estrogen

Question 8

onset of pubic hair growth around age 12

Answer 8

pubarche

Question 9

pubarche normally precedes menarche by____

Answer 9

2 years

Question 10

when does menarche usu occur?

Answer 10

age 12-13

Question 11

how long does it take for regular ovulatory menstrual cycles to occur?

Answer 11

2 yrs

Question 12

FSH is responsible for synthesis of____, whereas LH is responsible for synthesis of ____

Answer 12

estrogen; progesterones & androgens

Question 13

vagine is ____cm at birth, grows ___cm during early childhood, incr to ____late childhood

Answer 13

4; 1; 7-8.5

Question 14

after menarche what happens to uterine corpus: cervix ratio?

Answer 14

3:1

Question 15

at what age does gnRH become enhanced during sleep

Answer 15

8

Question 16

growth peak is ___years after breast budding and ___year before menarache

Answer 16

2; 1

Question 17

sexual maturation typically takes____yrs

Answer 17

4.5

Question 18

precocious puberty is defined as breast development before___, pubic hair before___, menstruation before____

Answer 18

age 7; age 8; age 10

Question 19

multiple bone fracures, cafe au lait spots, gnrh independent precocious puberty

Answer 19

mccune albright syndrome

Question 20

tx of choice for GnRH dependent precocious puberty

Answer 20

GnRH agonists

Question 21

best assessment for skeletal maturation?

Answer 21

bone age

Question 22

delayed puberty is no secondary sex characteristics by____; no menarche by____, no menses initiation ____after thelarche

Answer 22

13 yo; 15-16 yo; 5 years

Question 23

most common cause of delayed puberty with incr FSH is

Answer 23

Turners syndrome

Question 24

tx of turners

Answer 24

1. GH initiated early
2. estrogen when puberty would normally start
3. delay progestins until Tanner stage IV

Question 25

most common tumor assc’d with delayed puberty

Answer 25

craniopharyngioma

Question 26

hypoplastic olfactory tracts, no secretion of gnRH from arcuate nucleus, no breast development

Answer 26

kallmann syndrome

Question 27

how to tx kallman syndrome

Answer 27

exogenous hormones or admin of pulsatile GnRH

Question 28

most common cause of primary ameorrhea in women with normal breast development

Answer 28

mullerian agenesis

Question 29

congenital absence of vagina, uterus, fallopian tubes; normal ovarian fxn

Answer 29

mullerian agenesis

Question 30

present with pelvic pain and bulging bluish vaginal introitus

Answer 30

imperforate hymen

Question 31

tanner stage: elevation of papilla only

Answer 31

stage B1

Question 32

tanner stage: elevation of breast, papilla as small mound, enlargement of areolar diameter

Answer 32

stage B2

Question 33

tanner stage: enlargement of breast & areola with no separation of contours

Answer 33

stage B3

Question 34

tanner stage: further enlargement with projection of areola and papilla to form a secondary mound above the level of the breast

Answer 34

stage B4

Question 35

tanner stage: projection of papilla only, resulting from recession of the areola to the general contour of the breast

Answer 35

stage B5

Question 36

tanner stage: no pubic hear

Answer 36

stage PH1

Question 37

tanner stage: sparse growth of long, slightly pigmented, downy hair, straight or only slightly curled, appearing chiefly along the labia

Answer 37

stage PH2

Question 38

tanner stage: hair darker, coarser, and curlier; spreads to extend sparsely over the junction of the pubes

Answer 38

stage PH3

Question 39

tanner stage: hair adult in type; spreads over the mons but not to the medial surface of the thighs

Answer 39

stage PH4

Question 40

tannder stage: adult hair in quantitity and type

Answer 40

stage PH5