breast disease Flashcards
unilateral nipple discharge is more likely benign or malignant
malignant
breast lump fixed to chest wall?
malignant
when a discrete mass is breast, what to use?
mammogram
duct ectasia: malignant or benign
benign, with no risk for malignancy
dilated duct that widens, duct walls thicken, duct fills with milky fluid
duct ectasia
most common benign breast tumor
fibroadenoma
when do lactating adenoma typically develop?
during pregnancy
most common cause of blood nipple discharge
intraductal papilloma
tx of intraductal papilloma
duct excision
tx of fibrocystic disease
- d/c estrogen
2. avoid caffeine
thrombophlebitis of thoraco-epigastric vein
mondor’s disease
if triple receptor negative breast cancer under age 60, what else should you test for?
BRCA
what (T) stage if carcinoma in situ (DCIS, LCIS, paget disease)
Tis
what (T) stage: tumor under 2 cm across
T1
what (T) stage: tumor > 2 cm across, but under 5 cm
T2
what (T) stage: tumor > 5 cm across
T3
(N) stage: 1-3 axillary LN
N1
(N) stage: 4-9 axillary LN
N2
(N) stage: spread to axillary LN & internal mammary nodes, or >10 axillary LN involved
N3
the most common type of breast cancer
invasive ductal carcinoma
____is used to tx ER+ cancer
tamoxifen
_____is used to tx HER2+ cancer
trastuzamab
what is dx is a woman presents with peau d’orange and erythema
punch biopsy for inflammatory breast cancer
starts in the milk ducts, spreads to nipple, causes a crusty scaly red nipple
paget disease of the nipple
women over the age ____should have what breast cancer screening?
> 40 yo; annual breast exam + mammogram
age 25-40 should have clinical breast exams how often
every 1-3 years
what is the BI-RAD system
breast imaging reportign and data system
BI-RAD: benign finding
BI-RAD 2
BI-RAD: suspicious for malignancy
BI-RAD 4
breast conservation tx for cancer consists of?
lumpectomy + sentinel LN biopsy + whole breast radiation tx
difference in survival b/w lumpectomy vs masectomy
no difference in survival if lumpectomy performed with radiation
effect of contralateral prophylactic masectomy on survival
no difference
