menopause Flashcards

1
Q

menopause is evidence by _____consecutive months with no menstrual bleeding

A

12

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2
Q

the period before menopause that is transition b/w reproductive to nonreproductive years

A

perimenopause

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3
Q

when the ovarian estrogen production fluctuates unpredictably

A

perimenopause

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4
Q

the time period during which the changes of menopause occur

A

climacteric

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5
Q

avg age of menopause

A

51

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6
Q

what happens to ovaries during menopausal transition

A

ovarian follicles become resistance to FSH stimulation

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7
Q

loss of PMS sx in menopause is due to loss of what hormone?

A

progesterone

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8
Q

what is the cardinal sx of vasomotor instabilty assc’d with perimenopause

A

hot flash

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9
Q

1 morbidity in menopausal women

A

osteoporosis

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10
Q

best way to assess for osteoporosis

A

DEXA

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11
Q

normal DEXA T score

A

under -1 SD

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12
Q

DEXA T score indicative of osteoporisis

A

> -2.5 SD

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13
Q

what type of tx can be used to slow osteoporosis

A

estrogen

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14
Q

estrogen aids in osteoporosis by ____osteoclast activity

A

decreasing

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15
Q

when to screen for osteoporosis before age 65 (7)

A
  1. h/o fragility fracture
  2. weight under 127 lbs
  3. medical causes of bone loss
  4. parental h/o hip fracture
  5. current smoker
  6. alcoholism
  7. RA
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16
Q

1 cause of morality in menopausal women

A

CV disease

17
Q

if a woman has a uterus, how to tx menopause

A

estrogen + progesterone

18
Q

if a woman has NO uterus, how to tx menopause

A

estrogen

19
Q

relationship b/w standard HRT and endometrial hyperplasia

A

incr unless progestin is added

20
Q

relationship b/w standard HRT and breast cancer

A

slight risk incr

21
Q

relationship b/w standard HRT and HTN

A

none

22
Q

relationship b/w standard HRT and stroke/MI

A

slight risk incr

23
Q

relationship b/w standard HRT and venous thrombosis

A

2x risk incr

24
Q

hormone tx should be used for how long?

A

under 5 yrs

25
Q

recommended amt Ca

A

1200-1500 mg

26
Q

SERMS have estrogen like effect on____ and ____

A

lipids and bones

27
Q

when menopause occurs spontaneously before age 40

A

premature ovarian failure

28
Q

tx of premature ovarian failure

A

HRT immediately