ovarian pathology Flashcards
presentation of ovarian disease (3)
- abd pain
- abnormal uterine bleeding
- bowel or bladder issues
incidence of cancer
endometrial > ovarian > cervical
which type of cancer has worst prognosis?
ovarian
most common ovarian mass in young women
follicular cyst
distension of unruptured graafian follicle, mulitple follicles
follicular cyst
cystic enlargement of corpus luteum with central hemorrhage; may mimic endometriosis
corpus luteum cyst
often bilateral, multiple, associated with choriocarcinoma & moles, gonadotropin stimulation
theca-lutein cyst
most common ovarian tumor in women 20-30 yo
dermoid cyst
when a dermoid cyst contains functional thyroid tissue
stuma ovarii
endometriosis within ovary with cyst formation; varies with menstrual cycle
endometrioid cyst
chocolate cyst
endometrioid cyst
most common ovarian tumor
serous cystadenoma
age 20-50, thin-walled, large single or multioculated cystic mass filled with serous fluid
serous cystadenoma
thin, translucent wall lined with tall, cilitated fallopian like epithelium cells
serous cystadenoma
linked to cervix, multiloculated, tall mucus secreting columnar epithelium
mucious cystadenoma
presentation with pelvic pain, dysmenorrhea, dyspareunia, complex mass on U/S
endometrioma
mass arising from growth of extopic endometrial tissue
endometrioma
uncommon adenofibroma with noduels of transitional type epithelial cells in a dense fibrous stroma
brenner tumor
pale yellow solid tumor with coffee bean nuclei on H&E
brenner tumor
triad of ovarian fibroma + ascites + hydrothorax
meigs syndrome
wat is meigs syndrome assc’d with?
fibroma
benign tumor; abnormal bleeding in post menopausal woman
thecoma
most common ovarian malignancy
serous cystadenocarcinoma
psammoma bodies; malignant ovarian tumor
serous cystadenocarcinoma
malignant; complex architecture, nuclear atypia, stromal invasion
mucinous cystadenocarcinoma
intraperitoneal accumulation of mucious material from ovarian or appendiceal tumor
pseudomyxoma peritonei
is granulosa cell tumor malignant or benign
malignant
call-exner bodies assc’d with
granulosa cell tumor
sheet of uniform friend egg cells, hCG+, elevated LDH
dysgerminoma
abnormal BHCG, shortness of breath, hemoptysis due to hematogenous spread to lungs
choriocarcinoma
which malignant tumor is very responsive to chemo?
choriocarcinoma
most common tumor in male infant/children
yolk sac tumor
schiller duval bodies that resemble glomeruli; AFP+
yolk sac tumor
mucin secreting signet cell adenocarcinoma with GI origin
krukenberg tumor