breast pathology

Question 1

what race has highest risk for breast cancer

Answer 1

Af Am

Question 2

most likely located of malignant breast tumors

Answer 2

upper outer quadrant

Question 3

what type of receptor has the worst prognosis

Answer 3

triple negative

Question 4

single most important prognostic factor

Answer 4

axillary LN involvement

Question 5

of types of invasive carcinoma, which is most common?

Answer 5

ductal carcinoma

Question 6

2nd most common type of invasive carcinoma?

Answer 6

lobular carcinoma

Question 7

stage 2 breast cancer has a 5 year survival of ____

Answer 7

75%

Question 8

what is the single most important prognositc factor

Answer 8

axillary LN involvement

Question 9

early malignancy that fills ductal lumen without basement membrane penetration

Answer 9

DCIS

Question 10

DCIS presents with what on mammography

Answer 10

microcalcifications

Question 11

subtype of DCIS with ductal caseous necrosis surrounded by cancer cells

Answer 11

comedocarcinoma

Question 12

ezcematous patches on nipples that results from underlying DCIS

Answer 12

paget disease

Question 13

large cells with clear halo

Answer 13

paget cells

Question 14

what has the worst prognosis

Answer 14

invasive ductal carcinoma

Question 15

firm, fibrous, rock hard mass with sharp margins

Answer 15

invasive ductal carcinoma

Question 16

small duct like or glandular cells with collagenous stroma

Answer 16

invasive ductal carcinoma

Question 17

bilateral with multiple lesions in the same location; orderly row of cells

Answer 17

invasive lobular carcinoma

Question 18

what type of invasive carcinoma: fleshy, cellular, lymphocytic infiltrate, good prognosis

Answer 18

medullary carcinoma

Question 19

what type of invasive carcinoma: dermal lymphatic invasion, peau d’orange, neoplastic cells block lymph drainage

Answer 19

inflammatory carcinoma

Question 20

most common tumor in patients under 35

Answer 20

fibroadenoma

Question 21

is fibroadenoma a precursor to cancer?

Answer 21

no

Question 22

small firm mobile mass with sharp edges

Answer 22

fibroadenoma

Question 23

small mass that grows in lactiferous ducts & beneath areola w/ serous/bloody nipple discharge

Answer 23

intraductal papilloma

Question 24

is intraductal papilloma a precursor to cancer?

Answer 24

yes, incr risk for breast cancer

Question 25

fast growing mas that forms from periductal stromal cells; leaf like projections, postmenopausal

Answer 25

phyllodes tumor

Question 26

most common cause of breast lumps age 25-menopause

Answer 26

proliferative breast disease

Question 27

incr acini and intralobular fibrosis; assc’d with calcification

Answer 27

sclerosing adenosis

Question 28

patients >30 yo, incr in #epithelial cell layers in terminal duct lobules

Answer 28

epithelial hyperplasia

Question 29

what pathogen is most commonly responsible for acute mastitis?

Answer 29

S aureus

Question 30

post trauma, mass in breast with abnormal calcification

Answer 30

fat necrosis with giant cells