endocrinology Flashcards

1
Q

avg duration of female monthly cycle

A

20-45 days

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2
Q

endometrial proliferation takes place during follicular or luteal phase?

A

follicular

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3
Q

follicular phase is followed by____, luteal phase is followed by_____

A

ovulation; menses

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4
Q

when does the corpus luteum form?

A

luteal phase

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5
Q

GnRH is released in what sort of manner?

A

pulsatile

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6
Q

there is a pulsatile release of LH every____

A

90 min

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7
Q

FSH rises ________

A

early in follicular phase

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8
Q

peak concentrations of steroids occur when?

A

right before ovulation

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9
Q

where are inhibin A & B synthesized?

A

granulosa cells of ovary

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10
Q

inhibin A is secreted from____, Inhibin B is secreted from____

A

corpus luteum; granulosa cells

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11
Q

inhibin B regulates ant pit to decr secretion of_____

A

FSH

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12
Q

follicular phase is associated with_____synthesis

A

estrogen

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13
Q

during the follicular phase, proliferation of the uterin endometrium is regulated by?

A

estrogen

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14
Q

what induces ovulation?

A

the surge of FSH & LH at day 14

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15
Q

what hormone is absoultely req’d for ovulation?

A

LH

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16
Q

what is a temporary endocrine gland?

A

corpus luteum

17
Q

when does the corpus luteum reach a mature state?

A

7-8 days following ovulation

18
Q

what is the regulatory hormone of steroid synthesis in luteal phase?

A

LH

19
Q

what is the regulatory hormone of steroid synthesis in follicular phase?

A

LH & FSH

20
Q

differentiation of the uterine endometrium is regulated by?

A

progesterone

21
Q

what exerts negative feedback at the end of the luteal pahse?

A
  1. progesterone

2. inhibin A

22
Q

break down of the zona pellucida

A

hatching

23
Q

trophoblastic cells of the blastocyst makes contact with endometrium

A

apposition

24
Q

trophoblasts differentiates into (2)

A
  1. cytotrophoblasts

2. syncytiotrophoblasts

25
Q

what cell types sends out protrusions and invades the endometrium

A

syncytiotrophoblasts

26
Q

what stimualtes ovarian steroidogenesis for 1st 8 weeks after implantation?

A

HcG

27
Q

when does hcg production peak?

A

10 weeks

28
Q

think of what hormone for growth, development, metabolism of fetus?

A

hpl

29
Q

what happens to hpl over the course of pregnancy?

A

increases

30
Q

_______produce both Hcg and hpl

A

syncytiotrophoblasts

31
Q

hpl starts getting secreted at ______

A

6 weeks

32
Q

CRH is produced by _____and____

A

syncytiotrophoblasts and trophoblasts

33
Q

what hormone induces the onset of labor and PG production?

A

CRH

34
Q

what hormone inhibs PG production and suppresses uterine contraction?

A

progesteron and 17-OH progesterone

35
Q

what provides substrates for estrogen synthesis?

A

DHEA