GTB, cervical cancer pathology

Question 1

ferilization of an empty ovum by one or 2 sperms

Answer 1

complete mole

Question 2

uterus distended by large, bizarre, gelatinous “placental” mass

Answer 2

compelte mole

Question 3

snowstorm image on U/S

Answer 3

complete mole

Question 4

bunch of grapes appearence on gross specimen

Answer 4

complete mole

Question 5

which GTD has fetal parts present

Answer 5

partial mole

Question 6

hcg is markedly increased in ____, and somewhat increased in____

Answer 6

compelte mole; partial mole

Question 7

irregular spotting of brown, bloody, foul fluid + elevated HCG

Answer 7

choriocarcinoma

Question 8

which type GTD manifests with no villi?

Answer 8

choriocarcinoma

Question 9

tx of choriocarcinoma

Answer 9

chemotx

Question 10

which GTD is characterized by low HCG levels?

Answer 10

placental site tumor

Question 11

endocervix is _____, whereas ectocervix i _____

Answer 11

columnar; squamous

Question 12

HPV _______ are oncogenic

Answer 12

HPV 16 & 18

Question 13

E6 inhibits

Answer 13

p53

Question 14

E7 inhibits

Answer 14

p52+ p21 +Rb

Question 15

most invasive cervical cancer is of what type?

Answer 15

squamous cell (80%)

Question 16

stage of cervical cancer: involvement of pelvic wall & lower third of vagina

Answer 16

stage III

Question 17

tage of cervical cancer: extension beyond pelvis, invasion of bladder +/- rectum, distand metastasis

Answer 17

stage IV