Psychological aspects of pain Flashcards
Pain =
unpleasant sensory and emotional experience associated with actual or potential tissue damage and expressed in terms of such damage
What role might acute pain have?
Protective
Self-limiting pain =
Acute
2 broad types of pain:
Nocicpetive
Neuropathic
Nociceptive pain is associated with =
Actual tissue damage
2 types of nocicpetive pain =
Visceral
Somatic
Somatic pain =
Easily localised and describes
Ex of somatic pain =
Fracture
Visceral pain =
Poorly localised and describes. Associated with activation of nociceptive of organs
How might visceral pain be described?
Aching, dull, burning
Neuropathic pain is associated with
Structural neural damage or abnomral processing
How might neuropathic pain be described?
sharp, stabbing, burning, shooting,
Which kind of pain doesn’t respond well to conventional analgesics?
Neuropathic
Time line: acute pain
< 3 months
Time line: chronic pain
> 3 months
Chronic pain:
> 3 months
unpredicatable, unknown circuitry, difficult to treat, not useful
Mechanisms by which a chronic pain state is established =
Peripheral senstisation
Central sensitiasaion
Central reorganisation
Peripheral sensitisation =
Tissue damage leads to release of neuropeptides and inflammatory mediators. This reduces the threshold for activation of peripheral receptors
Central sensitisation =
Increased primary afferent release of glutamate and substance P activated NDMA receptors. Winds up CNS so it is hyperactive
Nociceptive neurotransmitters
Glutamate
Substance P
Pain receptor =
NDMA
Hyperalgesia =
exaggerate pain response
Allodynia =
Pain response to non-painful stimuli
Central reorganisation =
Changes to dorsal spinal cord and cortical sensory matrix