Approach to patients with CNS disorders Flashcards

1
Q

Frontal lobe is involved in =

A
Intellectual function
Praxis
Motor function
Inhibition
Bladder continence
Saccadic eye movements 
Broca's area - expression of language
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2
Q

Praxis =

A

Conception and planning of a new action, the performance of an action

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3
Q

Difficulty in activites requiring coordination and movement =

A

Dyspraxia

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4
Q

Internal capsule separates =

A

Thalamus, caudate nucleus and globus pallidus/putamen

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5
Q

In the motor homonculus, what is most lateral?

A

Face - arm

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6
Q

In the motor homonculus what is msot medial?

A

Lower limb

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7
Q

Pre-central gyrus =

A

Primary motor cortex

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8
Q

Post-central gyrus =

A

Primary sensory cortex

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9
Q

Problem with Broca’s area =

A

Expressive dysphasia

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10
Q

Where does the majority of the corticospinal tract decussate?

A

Medullary pyramids

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11
Q

What does the corticospinal tract split into?

A

Lateral, anterior

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12
Q

Lateral corticospinal tract =

A

Distal, fine movements (voluntary)

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13
Q

Anterior corticospinal tract =

A

Proximal muscles

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14
Q

lesion in the right motor cortex/right internal capsule will lead to what?

A

left sided upper motor neurone weakness

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15
Q

Lesion to right cranial nerve nuclei in brainstem causes:

A

Right sided lower motor neurone weakness

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16
Q

Temporal lobe is involved in:

A
Memory
Smell
Auditory cortex
Vestibular
Emotion 
Wernickes
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17
Q

Occipital lobe is involved in:

A

Vision

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18
Q

Lesion in the occipital lobe causes what?

A

Contralateral homonymous hemianopia

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19
Q

Parietal lobe is involved in:

A

Sensory integration

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20
Q

Wernickes area problem =

A

Expressive dysphasia

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21
Q

Dysphasia vs dysarthria =

A
Dysphasia = langusage
Dysarthria = words
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22
Q

Lesion in dominant parietal lobe:

A

Dyslexia
Acalculia
Poor left-right discrimination
Agnosia

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23
Q

Spinothalamic tract carries what modalities:

A

Pain, temperature, crude touch

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24
Q

Spinothalamic tract splits into

A

Anterior (crude touch)

Lateral (pain, temp)

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25
Where does the spinothalamic tract decussate?
About 2 spinal levels above entry - early!
26
DCML carries what modalities
Fine touch, pressure, vibration
27
Fasiculus cuneatus =
info from upper body
28
Fasiculus gracillis
info from lower body
29
Where does DCML decussate?
Medulla
30
Spinocerebellar tract remains
Ipsilateral
31
What does the spinocerebellar tract carry
Conscious proprioception
32
Why do lesions in the spinocerebellar tract often not show?
Damaged with other tracts - weakness usually disguises any loss of coordination
33
Brown-sequard syndrome:
Damage to 1 side of spinal cord: ipsilateral posterior column loss contralateral spinothalamic loss
34
Lesion in cortex, internal capsule or thalamus does what to tracts?
full contralateral sensory deficit
35
Weber syndrome is also known as
Midbrain syndrome
36
Weber syndrome effects which CN
CN III
37
Wallenburg syndrome also known as
Lateral medullary syndrome
38
3 zones of cerebellum and functions:
``` cerebrocerebellum = planning movements and motor learning, fine motor spinocerebllum = postural tone, correcting movements vestibulocerebellum = balance ```
39
Acronym to remember features of cerebellar dysfunction:
VANISH'D
40
VANISH'D =
``` Vertigo Ataxia Nystagmus Intention tremor Slurred speech Hypotonia Dysmetria (past-posting), dysdiadochokinesis ```
41
Most malignant primary brain tumour =
Glioblastoma multiforme
42
Features of a complete CN III plasy =
Eyes down and out Mydriasis Partial ptosis
43
Why is the ptosis in CNIII plasey only partial?
Lost levator palpebrase superioris but not Muller's muscle (which has sympathetic innervation)
44
Horner's syndrome is due to problems with which nerve supply?
Sympathetic
45
Symptoms of horner's syndrome:
Miosis Ptosis Anhydrosis Enopthalmos
46
Causes of horner's
Idiopathic C8/T1 pathology Carotid dissection Pancoast tumor
47
Features of a CN IV plasy =
eyes cannot look down
48
Features of an CN VI palsy:
Eye in, diplopia
49
Diplopia =
Double vision
50
CN VI plasy can be indicitive of:
Pons lesion, infarction
51
Facial UMN vs LMN lesion:
UMN: only bottom half effected, upper face has a dual nerve supply LMN: both halves effected
52
Bells palsy is a what lesion of what nerve
LMN lesion of CN VII
53
Bells palsy effects what parts of face?
Both halves on ipsilateral side
54
Plasy of facial nerve features:
``` Ipsilateral wekaness of muscles on top and bottom of face Incomplete eye closure Abnormal taste sensation on ant 2/3rds Hyperacussis Decreased lacrimation and saliva ```
55
Why might CN VII plasy cause hyperacussis?
Supplies the stapedius nerve (one of the ossicles)
56
Features of CN XI plasy:
difficulty shrugging, paralysis of sternocleidomastoid
57
Features of CN XII plasy:
``` Wasting of tongue Fasiculations Weakness of tongue Tongue deviates to side of lesion Dysarthria ```
58
Tongue in LMN lesion points
towards side of lesion
59
Tongue in UMN lesion points
away from side of lesion
60
Ex of tone pathologies:
Cog-wheel Clasp-knife Lead pipe
61
2 types of rigiditiy associated with Parkinson's
Cog-wheel | Leadpipe
62
What is used to grade power?
MRC scale
63
MRC scale goes from:
0-5
64
MRC scale =
``` 0- no movement 1- flicker of movement 2- movement with gravity eliminated 3- movement against gravity 4- movement against resistance 5- normal power ```
65
Examples of LMN lesion areas:
``` anterior horn nerve root brachial, lumbar plexus named nerve NMJ muscle ```
66
Romberg's test assesses
Vestibular function. patient stands with feet together and closes eyes. patient will wobble and lose balance with vestibular dysfunction