Psychiatry Flashcards

1
Q

Quetiapine (atypical antipsychotic) effect on weight

A

Promotes weight gain

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2
Q

First line treatment for obesity

A

Lifestyle intervention (CBT, diet, physical activity)

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3
Q

Unipolar mood disorders

A

Only low moods (depression)

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4
Q

The most strongly heritable mental illness is

A

Bipolar disease, 10x increase in 1st degree relatives

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5
Q

Mania in Bipolar I

A

Often extreme, increased mood and activity for more than 7 days

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6
Q

Mania in bipolar II

A

Hypomania, more than 4 days to count

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7
Q

Mania is defined as 3 or more of

A

Grandiosity, sleep decrease, speech change, racing thoughts, distractibility, agitation, impulsivity

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8
Q

Flight of ideas

A

Jumping from one idea to the next

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9
Q

DDX suspected mania

A

Hypomania, psychosis, substance use, delirium, catatonia, anxiety, endocrine, neurological, cerebrovascular

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10
Q

Chance of recurrence after first manic episode

A

90%

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11
Q

Treating mania

A

Requires medication and almost always hospitalization

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12
Q

Gold standard treatment for bipolar 1

A

Lithium

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13
Q

Lithium treats

A

BPD1, and can be helpful in BPD2

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14
Q

Can a breastfeeding woman take lithium?

A

No, lithium is contraindicated during breastfeeding

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15
Q

Which organ function can be reduced by lithium

A

Both thyroid and renal function (if used long term)

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16
Q

Divalproex sodium is also known as

A

Valproic acid

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17
Q

Med class Valproic acid

A

Anti-epileptic, can also be helpful in BPD

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18
Q

Can a pregnant woman take Valproic acid?

A

No, it is contraindicated

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19
Q

Main indication for Lamotrigine is

A

bipolar depression

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20
Q

Lamotrigine has a risk of which side effect

A

SJS - drug emergent rash

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21
Q

4 commonly used atypical antipsychotics include

A

Quetiapine, olanzapine, risperidone, aripiprazole

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22
Q

First line treatment for acute mania

A

Lithium, divalproex

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23
Q

First line treatment for bipolar depression

A

Lithium, Lamotrigine, Quetiapine

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24
Q

Overdose of TCAs can cause death by

A

Cardiac arrhythmia

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25
Q

How long til some benefit of antidepressants are seen?

A

2-3 weeks

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26
Q

How long until maximal benefit of antidepressants?

A

6-8 weeks

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27
Q

SADPERSONS for

A

Suicide and self harm behaviour

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28
Q

SADPERSONS stands for

A
Sex (male)
Age (<19, >45)
Depression 
Previous attempt 
Ethanol 
Rational thinking loss 
Social 
Organized plan 
No spouse 
Sickness
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29
Q

SIGECAPS screens for

A

Depression

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30
Q

SIGECAPS stands for

A
Sleep 
Interest 
Guilt 
Energy 
Concentration 
Appetite 
Psychomotor 
Suicidal ideation
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31
Q

How does ECT work for depression?

A

ECT induces generalized seizures

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32
Q

Most common side effect of ECT

A

Anterograde memory loss

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33
Q

Risperidone is commonly used to treat

A

Schizophrenia, bipolar disorder, irratability associated with autistic disorder

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34
Q

Risperidone class

A

Second generation atypical antipsychotic

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35
Q

Trying to conceive on risperidone

A

May cause hyperprolactinemia, which may cause a reversible decrease in reproductive function

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36
Q

Mechanism of action Risperidone

A

High 5HT2 and D2 receptor antagonists

Serotonin and dopamine receptor antagonist

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37
Q

Form 1 basic definition

A

Application for psych assessment

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38
Q

Form 1 is completed by

A

An MD

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39
Q

Form 1 is valid up to

A

72 hours

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40
Q

Form 42 basic definition

A

Notice to patient that theyre on a form 1 and why

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41
Q

Form 42 is completed by

A

MD, given to patient

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42
Q

Form 2 basic definition

A

Order for examination

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43
Q

Form 2 filled out by

A

Justice of the peace, based on information from public, family, friend, loved ones

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44
Q

Form 2 is valid for

A

7 days

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45
Q

When a patient arrives due to form 2

A

They must be assessed then placed on form 1, admitted voluntarily, or allowed to leave

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46
Q

Form 3 basic definition

A

Certificate of involuntary admission

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47
Q

Form 3 can last

A

Up to 14 days

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48
Q

Form 3 must be signed by

A

A different doctor than the form 1, a psych consult

49
Q

Form 30 basic definition

A

Notifies the patient theyre on a form 3, and why, and what their rights are

50
Q

PTSD first line treatments

A

Trauma focused CBT and antidepressants (SSRI/SNRI)

51
Q

PTSD related nightmares can be treated with

A

Prazosin - alpha blocker

52
Q

In what case of cognitive impairment would you choose to order CSF in investigations?

A

If it is early onset

53
Q

Routine imaging for cognitive impairment

A

Brain CT or MRI

54
Q

Routine lab testing with cognitive impairment

A

CBC, B12, TSH, CMP

55
Q

Initial workup for suspected dementia should include

A

Neuropsychological testing, lab work, and imaging

56
Q

Adjustment disorder is

A

Mood and behaviour symptom onset within 3m of an identifiable stressor

57
Q

Management for adjustment disorder is

A

Psychotherapy with adjunctive pharmacotherapy (short term sleep aids, or anxiolytics)

58
Q

Personalization

A

Seeing yourself as the cause of some negative external event for which you were not primarily responsible

59
Q

What % of personality traits are inherited?

A

40-60%

60
Q

Cluster A personality disorders “odd and eccentric” (3)

A

Paranoid, schizoid, schizotypal

61
Q

Cluster B personality disorders “dramatic, emotional, erratic” (4)

A

Histrionic, narcissistic, antisocial, borderline

62
Q

Cluster C personality disorders “anxious, fearful” (3)

A

Avoidant, dependent, obsessive compulsive

63
Q

Most common personality disorder is

A

Obsessive compulsive personality disorder

64
Q

Define obsessive compulsive personality disorder

A

Pervasive pattern of perfectionism, inflexibility, and need for control, stable course over time

65
Q

Major depressive disorder Sx must be present for

A

2+ weeks

66
Q

How many Sx does a person need for diagnosing MDD?

A

5/9 with 1 being mood/adhedonia

67
Q

Escitalopram, citalopram, sertraline, fluoxetine, paroxetine, fluvoxamine are from the class

A

SSRI antidepressants

68
Q

Venlafaxine, desvenlafaxine, duloxetine are from the class

A

SNRI antidepressants

69
Q

Bupropion drug class

A

NDRI

70
Q

Mirtazapine drug class

A

NaSSA

71
Q

Trazodone drug class

A

SARI

72
Q

Amitriptyline, nortryptiline, desipramine, imipramine, clomipramine drug class

A

Tricyclics antidepressants

73
Q

Phenelzine drug class

A

MAOI

74
Q

What is behavioural inhibition

A

Distress and withdrawal from unfamiliar situations which can develop into anxiety

75
Q

Primary coping strategy in anxiety is

A

Avoidance

76
Q

Main cause of disability in anxiety is

A

Avoidance

77
Q

Panic disorder is

A

Recurrent unexpected panic attacks in the absence of triggers

78
Q

Agoraphobia is

A

Marked unreasonable fear about a situation with active avoidance of that situation

79
Q

Generalized anxiety disorder is

A

Excessive anxiety about multiple events or activities accompanied by somatic symptoms, symptoms tend to overlap with depression

80
Q

Positive psychiatric symptoms are

A

Excess or distortion of normal function or experience

81
Q

Examples of positive psych symptoms

A

Delusions, hallucinations, disorganized thinking, abnormal motor behaviour

82
Q

Negative psych symptoms

A

Diminished or absent normal function

83
Q

Negative psych symptom examples

A

Affect diminished, avolition (loss of initiative), alogia (reduced speech), anhedonia (loss of enjoyment)

84
Q

Define delusions

A

Fixed false beliefs that arent changeable despite evidence

85
Q

Bizzare delusions differ from non bizzare because

A

They are clearly implausible

86
Q

How long must schizophrenia sx last to be diagnosed?

A

6m+

87
Q

MRI findings in schizophrenia

A

Frontal lobe smaller, bigger lateral and third ventricles than average

88
Q

1st generation antipsychotics work as

A

Potent DA D2 blockers

89
Q

2nd gen antipsychotics work by

A

Combination of D2 and 5HT blocking

90
Q

Side effects common to type 1 antipsychotics

A

Extra pyramidal/motor side effects like dystonia, Parkinsonism, tardive dyskinesia

91
Q

Side effects of second gen antipsychotics

A

Increased BMI, lipid abnormalities, diabetes

92
Q

Clozapine has a higher risk of which side effect amongst antipsychotics

A

Agranulocytosis

93
Q

Schizoeffective disorder is like schizophrenia but

A

The delusions and hallucinations last 2+ weeks, there must be a mood issue, and psychosis

94
Q

Delusional disorder definition

A

One or more delusions persistent for more than a month, not markedly impaired

95
Q

Schizophreniform disorder is just like schizophrenia but

A

Between 1 month and 6 months duration

96
Q

Brief psychotic disorder duration is

A

At least a day, less than a month

97
Q

Drugs that can cause psychosis

A

Cannabis, stimulants, hallucinogens

98
Q

Medical issues that can cause psychosis

A

Delirium, structural (tumour/stroke), degeneration (huntingtons/parkinsons), epilepsy, endocrine, infections

99
Q

DBT for BPD focuses on

A

Decreasing self harm and impulsivity, increasing ability to cope

100
Q

Acute stress disorder is like PTSD but…

A

Less than 6m (more than 1m)

101
Q

Adjustment disorder

A

Maladaptive reaction to a stressor, condition remits within 6m of the stressor resolving

102
Q

Alcohol or benzo withdrawal is treated commonly with

A

Diazepam

103
Q

Which benzos bypass liver metabolism?

A

Lorazepam, oxazepam, temazepam

104
Q

Medications used to reduce alcoholism (3)

A

Naltrexone, acamprosate, disulfiram

105
Q

Three treatment options for tobacco use disorder

A

Nicotine replacement therapy, bupropion, varenicline

106
Q

After a suicide attempt, someone who wishes they died is

A

3x more likely to attempt suicide in a short time interval

107
Q

Fitness to stand trial has 3 components

A

Understanding the nature and object of the hearing, possible consequences of the hearing, and can communicate with counsel

108
Q

Duty to warn and protect (3 factors)

A

Identifiable target, seriousness, imminence

109
Q

What are two main types of ADHD

A

Inattention and hyperactivity, Sx for 6m

110
Q

Labeling

A

An extreme form of over generalization “I’m a total idiot”

111
Q

Over generalization

A

Seeing one negative event as proof of a never ending pattern

111
Q

Fortune telling

A

Anticipating that things will turn out badly, and this is a fact

111
Q

Catastrophizing

A

Exaggerating the importance of negative things and the likelihood of a disastrous outcome

112
Q

Which antidepressant is associated with dose dependent hypertension

A

Venlafaxine

113
Q

MAOI hypertensive crisis refers to

A

Severe hypertension after patients on MAOIs ingest foods containing tyramine (sympathomimetic)

114
Q

Patients treated with lithium need to be monitored for

A

Hypothyroidism

115
Q

Treating lithium induced hypothyroidism

A

T4 supplementation

116
Q

Circadian rhythm sleep wake disorder characterized by sleep onset insomnia and excessive morning sleepiness

A

Delayed sleep wake phase disorder

117
Q

Circadian rhythm disorder characterized by inability to stay awake in the evening and early morning insomnia

A

Advanced sleep wake phase disorder