Psych: Stimulants Flashcards
How do stimulants work for ADHD?
Block reuptake of monoamines via VMAT and increase NT release (NE, DA, and 5HT)
What are some common side effects of stimulants? (6)
GI Upset Headache Decrease Appetite (weight loss and reduced growth) Insomnia Anxiety Elevated BP
What is the most serious rare effect of stimulants?
Sudden cardiac death
What is a unique side effect of stimulants that involves the skin?
Chemical Leukoderma
-with Daytrana patch
What stimulants are used to treat ADHD that are amphetamine derivatives? (5)
Amphetamine
Dextroamphetamine
Lisdexamfetamine
Methylphenidate
Dexmethylphenidate
What are some non-stimulants used for ADHD? (3)
Atomoxetine
Guanfacine and Clonidine (α2 agonists)
How fast is the onset of most stimulants?
24 hours
Are stimulants available to pick up without doctor’s orders?
No, controlled substance (1 month supply)
-most states allow 3 months (not MO though)
What form of medication does dextroamphetamine/AMP/Adderal come in and how long does it last??
Tablet
-immediate release (4-6 hr)
What form of medication does dextroamphetamine sulfate/Procentral come in and how long does it last??
Liquid
-immediate release (4-6 hr)
What form of medication does amphetamine sulfate/Evekeo come in and how long does it last??
Capsule
-immediate release (4-6 hr)
What form of medication does dextroamphetamine/Zenzidi come in and how long does it last??
Tablet
-immediate release (4-6 hr)
What form of medication does dextroamphetamine/Adderall XR come in and how long does it last??
Capsule
-extended release (8-12 hrs)
What form of medication does dextroamphetamine/Dexedrine come in and how long does it last?
Capsule
-extended release (8-10hrs)
What form of medication does amphetamine/Dyanavel XR come in and how long does it last?
Liquid**
-Extended release (13 hrs)
great for people who cannot swallow well
What form of medication does lisdexamfetamine/Vyvanse come in and how long does it last?
Capsule
-extended release (10-12hrs)
What form of medication does Amphetamine/Mydayis come in and how long does it last?
Capsule
-extended release (16hrs**)
What form of medication does dexmethylphenidate/Focalin come in and how long does it last?
Tablet
-immediate release (4-6 hr)
What form of medication does methylphenidate/methylin oral solution come in and how long does it last?
Liquid
-immediate release (3-4hrs)
What form of medication does methylphenidate/ritalin come in and how long does it last?
Tablet
-immediate release (3-4hrs)
What form of Adzenys come in and how long does it last?
Extended release, oral dissolving tablet
-no water necessary
What form of medication does methylphenidate/ritalin-SR come in and how long does it last?
Tablet
-Sustained release (4-8hrs)
What form of medication does methamphetamine/Desoxyn come in and how long does it last?
Tablet
-Sustained release (4-8hrs)
What form of medication does methylphenidate/aptensio XR come in and how long does it last?
Capsule
-Extended release (12 hrs)
What form of medication does methylphenidate HCl/Concerta come in and how long does it last?
Tablet
-Extended release (10-12hrs)
What form of medication does methylphenidate ER/comtempla XR-ODT come in and how long does it last?
Tablet
-Extended release (12 hrs)
What form of medication does methylphenidate transdermal/Daytrana come in and how long does it last?
Transdermal patch**
-Extended release (10-12hrs)
What form of medication does dexmethylphenidate HCl/Focalin XR come in and how long does it last?
Capsule
-Extended release (6-10hrs)
What form of medication does methylphenidate HCl/metadate CD come in and how long does it last?
Capsule
-Extended release (8-10hrs)
What form of medication does methylphenidate HCl ER/ritalin LA come in and how long does it last?
Capulse
-Extended release (8-10hrs)
What form of medication does methylphenidate HCl/QuilliChew come in and how long does it last?
Chewable tablet**
-Extended release (8hrs)
What form of medication does methylphenidate/Quillivant XR come in and how long does it last?
Liquid **
-Extended release (8, 10, 12hrs)
MOA of atomoxetine?
Blocks NET reuptake of NorE
MOA of guanfacine/clonidine?
Agonist of CNS α2
Onset of activity for non-stimulants?
1-4+weeks
-in contrast to stimulants (24hrs)
Why are non-stimulants used?
Useful for patients that are intolerant to stimulant effects
What form of medication does atomoxetine come in and how long does it last?
Capsule
-24 hours
What form of medication does clonidine come in and how long does it last?
Tablet
-12-24hrs
What form of medication does Guanfacine come in and how long does it last?
Tablet
-12-24hrs
Should you crush, chew, or break the tablets of guanfacine or clonidine?
nope
What BP effect happens when you stop taking clonidine and guanfacine?
Rebound HTN