GI: Oddly Specific Hep Pharm Qs Flashcards
Which HepB drugs can you use in toddlers?
Entecavir-2 yo!
Which HepB drugs can you use if the pt is less than 18?
Entecavir (2) and Tenofovir, Adefovir(12)
Which hepB drug causes steatosis?
Tenofovir
Precautions when using Tenofovir?
Renal Impairment: renal failure and Fanconi syndrome
Which HepB drug can increase creatinine after lamivudine resistant liver transplants?
Adefovir
-it is nephrotoxic!
Which HepB drug increases creatine kinase?
Telbivudine
-any many other reactions
Arthralgias, back pain, pyrexia, dyspepsia to name some
Can you use Peg IFN alfa in neonates?
No
What is the BB warning for Peg IFN alfa-2b?
Fatal or life threatining neuropsychiatric, autoimmune, ischemic, and infectious disorders
Can you use PEG IFN-alfa 2b in kids?
Nope, only after 18 if they are HepC positive
Can you use Velpatasvir/Sofosbuvir in kids?
No, only adults with chronic HepC
When can you use Velpatasvir/Sofosbuvir in decompensated cirrhosis?
In combo with Ribavirin
What is decompensated cirrhosis?
It just means the liver has cirrhosis, and is not able to still function and produce all the actual liver function tests
I don’t know how tricky hes going to get, so I figured knowing what it is would be nice.
Can you use Ribivarin if the patient has B-thalassemia?
No, hemoglobinopathies are contraindicated with Ribavarin
If a patient has a history of blood exposure to HepC, which drug can you prescribe?
Ribivarin
Which HepB drugs can be used to treat patients who are 5yo+?
Ribivarin + IFN-alfa-2a
ONLY HEPB DRUGS TO TREAT KIDS.
