PROSTATE CANCER Flashcards

1
Q

Prostate cancer is common in men

A

over 50

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2
Q

95% of prostate cancer is

A

ADENOCARCINOMA

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3
Q

most common cancer diagnosed in men

A

prostate cancer

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4
Q

____ leading cause of cancer deaths is prostate cancer

A

2nd

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5
Q

____ most common male malignancy world wide

A

4th

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6
Q

level standard for prostate cancer testing

A

PSA and DRE

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7
Q

20-40% of men with prostate cancer will have

A

normal PSA level

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8
Q

PSA density is

A

ratio of PSA to prostate volume

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9
Q

PSA variants

A

PSA density
PSA velocity
Free/total PSA ratio

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10
Q

indications for initial biopsy (4)

A

Abnormal DRE, TRU, PSA, mets

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11
Q

first biopsy takes how many samples

A

10-12 + suspicous area

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12
Q

repeat biopsy done when

A

negative but PSA more than 10, atypical cell, small so might have missed, and active surveillance

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13
Q

repeat biopsy # of samples

A

13 to 15

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14
Q

most cancer found where

A

peripheral

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15
Q

position for guided biopsy

A

left lateral decub

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16
Q

how far does biopsy needle go in

17
Q

side effects of biopsy

A

blood in urine, stool and sperm for days

discoloured ejaculate for months

18
Q

singnificant side effects of biopsy

A

sepsis, large hematoma, urinary retention, significant rectal bleeding

19
Q

why is cancer difficult to detect in the inner gland

A

heterogenous and BPH nodules

20
Q

hardest tumor to detect

A

anterior midline tumor

21
Q

classic cancer appearance

A

hypoechoic nodule

22
Q

_____-_____% of cancer not detectable

23
Q

__% of cancer is isoechoic

24
Q

alternative cancer appearance

A

can replace entire peripheral zone making peripheral zone more hypoechoic than inner
\

25
what is staging
extent of the disease
26
two types of staging
clinical and pathological
27
clinical staging important for
deciding patient management
28
cTX
can not be assessed
29
cT0
no evidence of tumor
30
CT1
Not palpable and not visible
31
cT2
Palpable and visible
32
cT3a
extended to periprostatic soft tissue
33
cT3b
extended to seminal vesicles
34
T4
TUMOR INVADED OTHER STRUCTURES
35
pathological staging considered
more accurate prognosis
36
pathologiclas staging requires (3)
evaluation of prostate, sv and lymph nodes
37
pT2
organ confined
38
pT3
extraprostatic extension
39
pT4
invasion of rectum, levator muscle ad or pelvic wall