Principles of Neuroscience Lecture 24 Brain Evolution Flashcards
What are the three ways we can compare brain size? Which is the most useful?
Size of brain
Brain to body weight ratio
Encephalisation factor - the most useful. This tells us how far off the average for the species’ size its brain is
What did Cuvier say about brain size?
All else being equal, smaller animals have a greater body to brain weight ratio
What is special about cartilaginous fish?
These have a very steep slope for the graph of brain vs. body weight
Describe differential regional size in the brain of different animals
In vertebrates, the relative sizes of different regions in the brain varies
Eg. Humans have, most importantly, a very large neocortex, whilst other animals have an olfactory lobe that is bigger than ours
What is meant by “a rat is a monkey is a human”?
This is saying that all these animals have the same functional regions in the brain, which are also organised in a similar way, they are just different sizes
Which area of the brain is fairly unique to higher animals?
Neocortex
How does brain architecture in simple, as well as very large animals, compare with human?
Not vastly different, as we might expect
Goldfish: everything that is present in humans is here, it is just more dense and miniature
Whale: lack the lamination that we see in humans
Describe differences in gyrification in different monkeys
As brain size and complexity increases, there is an increase in gyrification
Describe differences of cortical thickness in different monkeys
As the brain size and complexity increases, there is no increase in the thickness of the cortical layer
What is special about hominids?
They have a very large brain, with a very large neocortex
What are the three different trajectories of brain vs. body weight?
Monkeys: not a steep slope
Australopithecines: also, they did not show a huge expansion in brain size over the years
Hominids: huge increase in brain size over the years
Why is a big brain better?
More cells
Better connectivity
Greater differentiation of cell types
Different cytoarchitecture
Describe migration of hominids
Out of Africa to Middle East, then Europe and Asia
What is interesting about Homo Florensis?
Despite being alive not that long ago, they had a tiny brain
On which trajectory is Homo Florensis? (Body vs. brain weight?)
It is ambiguous, we can’t tell whether it is a hominid or an Australopithecine