Previous exam 2006 Flashcards

1
Q

What are levels of evidence

A

Level of Evidence A: data derived from multiple randomized clinical trials of meta-analyses
Level of Evidence B: data from a single randomized trial, or nonrandomized studies
Level of Evidence C: only consensus opinion of experts, cases studies, or standard-of-care.

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2
Q

Female with right heart dysfunction now post op MVR with PA pressures 85/50. What are 4 specific interventions you would do

A

Principles:
Optimize preload
Minimize afterload (particulary the RV)
4 specific interventions
Administer fluid for PCWP 15 to 20
Nitroglycerine/nitroprussed for afterload reduction
Mirinone for reduction of PAP, inotropy, lusitropy
Inhaled nitric oxide
optimize O2/pH/Co2

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3
Q

Patient with RCA infarction post CABG–cannot wean from RVAD. List 3 possible recovery pathways

A

Bridge to recovery

Long-term VAD

Bridge to transplant

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4
Q

What is a protocol for weaning off RVAD

A

Start to wean when CI > 2.9 and no increase in PCWP when flow rate dropped by 50%. Then drop 25% further and assess PCWP.

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5
Q

How do you calculate pulmonary vascular resistnace

A

Mean PA pressure - LA pressure divuded by CO

measures in Dynes.

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6
Q

What degree of PVR do you intervene

A

PVR > 80 do not repair
PVR 6 to 8 do vasodilatory challenge
PVR < 6 then it’s ok

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7
Q

LVAD placement, output falls 12 hours after surgery: Give 4 possible cuases

A

Bleeding as a result of tamponade
RV failure
Device failure
Hypovolemia

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8
Q

4 clinical features of tamponade

A

Hypotension
Tachycardia
Low urine output
cold peripheral

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9
Q

4 hemodynamic features of tamponade

A
increased filling pressures
equalization of filling pressures
pulsus paradoxus 
low cardiac output
Right atrium and right ventricular 
increased JVP 
respiratory variation in TV/MV inflow 
CVO tracing: attenuated y descent (reduced atrial filling) with or without prominent x
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10
Q

List 5 ways to assess athersclerosis of the aorta

A
Palpatin 
chest x-ray
aortogram
CT chest
TEE 
Epiaortic echo
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11
Q

5 ways of dealing with porcelain aorta identified in the OR

A

cancel the case
Off pump LITA, RITA, with SVG with prximal contructed to LITA or innominate artery
Off pump beating assisted (cannulate femorial or axillary artery) and use off pump technique
Fibrillatory arrest–provided no AI
May perform only LIMA to LAD and do PCI to remainder
Replacing the ascending aorta under circulatory arrest and then do CABG

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12
Q

For off pump CABG lsit 3 things that are equivocal and list 5 things that are less with OPCABG

A
3 things that are equivocal
	30 day mortality
	stroke rate
	myocardial infarction 
5 things that are less with OPCABG
	post op AF
	red cell transfusion 
	less inotropes
	length of stay
	few distalas
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13
Q

3 advantages of bicaval anastomosis in transplant

A

Less TR and MR
Less atrial arrhythmias and conduction disturbance
shorter hospital stay
reduced postoperative dependence on diuretics
Less RV dysfunction

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14
Q

List 6 clinical bedside test

A
No response to pain
apnea 
absecene of brain stem reflexes (doll's eyes, caloric reflex test, pupils dilated) 
Bedside ECG 
sensory evoked potentials
ensure no metabolic disturbances, pharmacologic agents, and hypothermia
cerebral angiography 
radionuclide cortical blood flow studies
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15
Q

10 complications of open PDA ligation

A
recurrent laryngeal nerve damage
chylothorax 
pnneumothorax
hemothorax
coarctatoin 
phrenic nerve injury 
ligation of PA, aorta 
residual flow
rupture/hemorrhage 
infection 
death
embolization
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16
Q

What is management of intra mural hematoma from LSCA to diaphragm;

A

IMH secondary to rupture of the vasa vasorum

Treat like type B dissection (BP control, operation for complication of type B such as contained rupture, malperfusion, progressive enlargement, persistent pain, and persistent hypetension

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17
Q

List 3 general physiologic derangements that can lead to tissue hypoxia and give an example of each

A

Low cardiac output (decrease deliver)
Anemia (decrease oxygen carrying capacity)
Hypoxemia: DO2 = Co x Hg x Sao2 + paO2

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18
Q

List 5 ways to repair the anterior leaflet of the mitral valve

A
triangular resection 
chordal transfer
neochordiae
alfieri stitch 
papillary muscle sliding or shortening 
chordal transpositoin from posterior leaflet
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19
Q

What is Custodiol cardioplegia

A

Intra-cellular solution
Crystalloid cardioplegia that contains histidine, trptophan, and ketoglutarate
histidine has a strong buffer effect which can prevent acidosis in cardiac myocytes
Low acting (2.5 hours)
30cc/kg in a single dose

20
Q

Left superior vena cava and mitral surgery

What structure does NOT involute with persistent LSVC

What can be absent with persisten LSVC

Where does it drain

List 2 ways to do venous cannulation

A

Does not involute—Left anterior cardinal vein

The innominate vein maybe absent

Drains into coronary sinus

Venous cannulation: LSVC, double cannulation on the right if no innominate, cannulate coronary sinus with big cannula and do vaccum assit

21
Q

Redo CABG–retrograde ongoing for 2 minutes–heart still beating. retrograde pressure is 40 with a flow of 60ml/min. What are two problems and how to correct

A

Problem # 1: Heart is still beating
Problem # 2: retrograde pressure is too low…should be 200ml/min. Could represent coroanry sinus becoming distended or that the cannula has entered the coronary vein.

Ways to solve this problem
Pull Canula back, increase flow, check K+, isolate and clamp lita, cool to 25 degrees C.

22
Q

Patient is post CAB. 4 different medication and rationale

A

ASA–benefit on graft occlusion–Mangaon NEJM 2002 (lower MI, mortality, lower stroke, lower renal failure, bowel infarction)
Cholesterol lowering agent: decrease risk of CV events at > 7 years “post CABG NEJM 1997)
Beta Blocker: significant decrease in AF
ACE: Apres, IMAGINE–lower incidence of CV events, angina, repeat revascularization

23
Q

FInish implanting a DDD pacemaker–nurses notices pt HR is 120 upper limit of device. List 3 possible causes

A

Pts own sinus rate at 120 (and device is at its upper limit)
Pt is in SVT (AF or A flutter)
Pacemaker-mediated tachycardia

24
Q

What is Pacemaker-mediated tachycardia

A

Occurs with DDD pacemakers–inadvertently cause a reentrant arrhythmia. retrograde conduction through the AV node, possibly triggered by a premature ventricular depolarization.

If pacemaker senses the resulting atrial depolarization and paces the ventricle, a recurring cycle us set up that could continue indefinetly at the upper rate limit of the pacemaker.

25
Q

What is treatment of pacemaker pocket infection: list 3 steps in management

A

prompt extraction of the device and leads

course of IV antibiotics

Device implantation at another site during a separate surgical procedure

26
Q

Antegrade List 2 advantages and disadvantages

A

Pro
Most physiologic efficient perfusion of the brain
Sequential perfusion of the cerebral arteries provides addtional safety to unilateral cerebral perfusion
improved cooling and oxygenation shown to decrease ischemic injury

Con: risk of dissection of the arterial wall–complex cannulation techniques
risk of embolism of atheromatous plaque material or air

27
Q

What is advantage and disadvantage of retrograde cerebral perfusion

A

Pro
Accepted facts in a supplement cooling of the brain hemisphers
Possible expulsion of solid particles or gaseous bubbles from the arch arteries

Con
distribution of retrograde flow is uneven, with a preferential distribution in the saggital sinus and hemisphere veins. The large steal of blood to the inferior venous territory is corroborated by the clinical finding of an extremely small proportion of perfused blood flowing out of the arch

Interstitial edema is another potential problem of retrograde perfusion, which can lead to cerebral edema and HTN, if [ressure gets over 25mmHg

No docuementd benefit over hypothermia alone

28
Q

Patient is a previous CABG and needs MVR and possible redo graft to RCA.

List 2 surgical incisions through which the operation can be done.

List 2 atrial incisions to approach the mitral valve…and advantage and disadvantage of each.

A

Redo sternotomy
Right anterior thoracotomy preferred approach is right throactotmy and transseptal atrial incision

Transeptal:
better for small LA size
increased suture line/greater risk of injury to arteries that supply SA node
Sondegaard grove: (left atrial incision)
less suture line
more difficult in small LA

29
Q

What are 2 indications to use radial artery for conduit in bypass

A

Young patients that you plan for total arterial revascularization and longer graft patenty

Lack of conduits, contra-indications to bilateral ITA

Need to source studies

30
Q

What are 3 contraindications to radial artery in general

A

Job restrictions
positive (poor Allens test)
Potential need for vasopressor (severe LV dysfunction)
renal failure needing fistual
Need for immediate high flow
Anatomical restrictions (not 70% stenosis on the left or > 90% on the right coronary systems)

31
Q

What are contraindications to use the LITA

A

Previous surgical damage
subclavian stenosis
Mediastinal irradiation
Leriche syndrome

32
Q

Benefits of skeletization

A
less pain
greater length
more flow
improved visualization 
easier to construct composite grafts
more sternal perfusion 
less sternal infection
33
Q

Name trial which showed PCI vs CABG in diabetics

A

BARI

5 year survival was 65.5% among patients treated with DM who were assigned PCI compared with 80% who were CABG

34
Q

What are important issues to consider for type A dissection

A

Location of tear: most common anterior aspect of the ascending aorta 3 -5 cm above the RCA ostium

Extent of resection:
Aortic valve replacement: if disease or severed by the dissection or BAV
Root: in case of tear into root, destructed annulus, connective tissue disorder

35
Q

AVR replacement with mechanical prostheis; used ostial cannulation; now can’t come off pump. List 3 possible problems

A

RV ischemia: RCA dissection; RCA embolic event (calcium/air)
LV ischemia: Left maim, LAD, or circumflex dissction or embolic event
LV stunning: inadquate protection (short LM with preferential perfusion of the LAD
RV stunning: inadequate protection (small RCA)

36
Q

IVDU–what is most common valve, pathogen, and 4 surgical options

A
Most common valve is Tricusid 
Most likely organism is S. Auerus
	Surgical options are 
Repair (vegetectomy and primary repair/debride bicuspidse/devega/
Replace
Valvectomy (remove it(
37
Q

What are indications and work out for a patient with early prosthetic valve endocarditis. Pt will present with microhematurai and mild leukocytosis and fever/chills

A

Early prosthetic valve endocarditis

obtain Echo and blood culture

Criteria for diagnosis: positive blood cultures, echo, fever, embolic, immunlogic.

early surgery for mild heart failure, S.aureus,

38
Q

Peri-infarct VF arrest with EF at 30%, revasculaize and EF returns to normal. What do you do about arrhythmia? What do you do if EF stays at 30%

A

2002 guidelines for implantation of AICD circulation

In revascularized patient with normal EF in who ventricular arrhythmia pre-op is attributable to an ischemic even , there is no indication for AICD

in patients with EF < 30% at least one month post MI or 3 months post CABG there is indication to implant AICD (IIa)

39
Q

5 year old kid with L-R shunt on echo; Name 5 indications for surgical intervention

A

Pulmonary to systemic flow ratio (Qp:Qs) 1.5:1
Uncontrolled CHF…growth failure, recurrent respiratory infection
Large asymptomatic defects associated with elevated PA pressure (PAP > 40 mmHg)
If the shunt results in prolapse of an aortic valve cusp
Ventricular enlargement/RV dysfunction

if PVR is fixed at 8-12 then operation is contraindicated

40
Q

Previous TOF repair with transannular patch. Name 5 late complications that would represent indications for surgical intervention.

A

Pulmonary valve regurgitation with fatigue and dyspnea/RV failure
Pulmonary valve regurgitation with ventricular arrhythmias
Pulmonary valve regurgitation with TR
persistent or recurrent RVOTO
residual or recurrent VSD
Large left to right shunt
aortic root dilation and aortic valve regurgitation > 55
Pseduo or aneursym of RVOT

41
Q

What are risk factors for PA rupture from PA cathf

A
Pulmonary HTN 
systemic anticoagulation
long term steroid use 
age older then 60 
Excessive cath manipulation 
balloon hyperinflation 
surgically induced hypothermia 
cardiac manipulation during surgery
cardiac decompression 

mortality near 70%

42
Q

What is treatment for PA rupture

A
Trancatheter embolization 
Urgent thoracotomy 
	lobectomy 
	pnemonectomy 
	hilar clmaping with direct arterial repair 
	PA ligation 

Adjunctive: lateral decubits; IV fluids; reverse anticoaglation, PEEP,

43
Q

List 4 indications for LV aneurysm repair

A
Symptoms
	angina
	CHF
	Ventricular arrhytmia
	embolism
Rupture with or without development of pseudoaneurysm
Congenital aneurysms--due to presumed risk of rupture
Documented expanion
44
Q

What drugs do you treat a type B dissection with

A

Sodium nitroprusside
direct arterial vasodilator and short onset and duration of action
ideal to rapidly achieve target SBP
Esmolol
Beta 1 selective with short half life
decreased inotropic state of myocardium and decreased heart rate
metoprolo, propanolo, and labetolo aer other options

45
Q

What is SAM, pathophysiology and 2 ways to manage it.

A

Develops in patients with excess leaflet tissue and a posterior mitral leaflet heigh of more than 1.5 cm. After mitral valve repair, line of leaflet coaptation is displaced anteriorly by redundant PML. Venturi effect pulls AML and coaptation point toward vetricular septum during systole and causes LVOT obstruction

Managment:
Give volume
avoid being hyperdyanmic
decreased inotropic
beta blocker
Back on bypass
Ensure annuloplasty band is of sufficient size and correct orientation
sliding posterior-leaflt valvuloplasty to move coatation point to a more posterior location
reduction of size of anterior leaflet by triagulat resection or plication
edge to edge repair of sewing A2 and P2, creating double orifice mitral valve
neochordal placement to pull posterior leaflet further

46
Q

Describe levels of evidence and associated grades of recommendations based on those levels

A

Class I: conditions for which there is evidence and/or general agreement that a given procedure or treatment is beneficial, useful, and effective.
Class II: conditions for which there is conflicting evidence and/or a divergence of opinion about the usefulness/efficacy of a procedure or treatment
Class IIa–weight of evidence in favour of usefulness
Class IIb less well established

Class III–conditions for which there is evidence and an/or general agreement that a procedure is not useful/effective an in some cases may be harmful.