max prediction for 2013 Flashcards

1
Q

Severe aortic stenosis

A
Risk of mortality over the next year
1% 
Likelihood of developing symptoms in the next year
33% at 2 yr, 14% at 1 yr
In aortic stenosis, what is the rate of decrease in valve area per year
0,1 cm2 
7 mmHg (mean)
0,3 m/s
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2
Q

What is classification of Ebsteins

A

A: Little S-P leaflet displacement, Ant leaflet N, small atrialized chamber, RV N
B: Moderate S-P leaflet displacement, Ant leaflet N but chord aN, large atrialized chamber with reduced contractility, reduce size RV
C: Severe S-P displacement, restricted Ant leaflet, large atrialized chamber with low contractility, small and hypocontractile RV
D: Sac, no ant leaflet mobility, infundibular RV

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3
Q

Secondary tricuspid regurg

List 3 pathophysiologic mechanisms and an example for each

A
Annular dilatation (dilatated CMP)
PHT (left lesion)
Leaflet restriction (ischemia)
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4
Q

What are indications for endocarditis prophalaxis

A

Prosthetic valve or material for repair
Previous infectious endocarditis
Cyanotic unrepaired or palliated
Repair congenital anomaly 6 months postop
Repair with residual defect close to prosthetic material
Transplanted patient with valvulopathy

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5
Q

What is outcome of FREEDOM

A

Primary endpoint is composite of death all cause, MI and stroke
26,6% in PCI and 18,7% in CABG

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6
Q

List 3 negative of hco3 in CPR

A

Metabolic alkalosis
Intracellular acidosis
Large osmotic load

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7
Q

PCI in SYNTAX 5Y (increase, decrease or same) vs CABG

A
MACCE : inc
Mortality : same
Stroke : same
MI : inc
Repeat revasc : inc
Cardiac mortality : inc
MACCE LM : same in SYNTAX <33, inc SYNTAX >33
MACCE 3VD : same in SYNTAX <22, inc SYNTAX >22
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8
Q

Mechanism and histology of micro re-entry in a fib

A

Mechanism: shortened atrial refractory period, atrial tissue heterogeneity, electrical remodeling leads to micro reentry.
histology : atrial fibrosis ,decreased muscle mass, inflammation

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9
Q

Class I indication of CABG to improve survival

A

LM
3VD with or without prox LAD
2VD with prox LAD
Survivor of sudden death with presumed ischemia mediated VT

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10
Q

Ischemic MR: recent literature states certain subgroups benefits with reverse LV remodeling.
List 4 preoperative pedictors that suggest improved remodeling after CABG + IMR repair

A

LVEDD < 65
LVESD < 51
Systolic sphericity index below 0.72
Wall motion score index score below 1.59

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11
Q

5 predictors for developing symptoms or adverse outcomes in AS

A
Advance age
CAD risk factors
Calcium
Peak jet velocity
Progression
Excessive LV hypertrophy
Symptoms on exercise testing
Increased natriuretic peptides
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12
Q

Spinal cord protection in thoracoabdominal

A
Partial or complete bypass
avoidance of hypotension/maintenance of MAP
avoidance of hyperglycemia
partial hypothermia
Reanastomosis of intercostals T7-T12
CSF drain
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13
Q

5 predictors of recurrent MR after ischemic MR repair

A
LVEDD >65
Posterior leaflet angle >45
Anterior leaflet angle >25
Tenting area >2,5 cm2
Coaptation distance >10mm
End systolic interpapillary muscle distance >20mm
Systolic shericity index >7
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14
Q

5 year freedom from death, symptoms and surgery in asymptomatic severe MR

A

70%

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15
Q

Sano shunt vs. modified BT shunt in Norwood operation

When blood flow occurred in coronaries and pulmonary arteries in both shunt.

A

Sano: coronaries in diastole and PA in systole

BT shunt: coronaries in diastole and PA in both

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16
Q

What are predictors of early SVG

A

Age <40
Hyperparathyroidism
Renal insufficiency

17
Q

What are predictors of RVAD placement after LVAD

A
Preop vasopressors
Preop ventilation support
Increased bilirubin
Increased creatinine
Increased BUN
Decreased RV stroke work index
Increased CVP/Wedge ratio
Increased CVP
18
Q

Patient with dilated cardiomyopathy (EF<20%). Has been on “state of the art” meds. Now patient has NYHA class 3-4 failure. List 4 “state of the art” meds patient was on. List 4 non-medical treatment options for this patient.

A

Beta blocker, ACEI, spironolactone, digoxin or lasix???

CRT, LVAD, transplant, ICD??

19
Q

Patient with LVEF 60%, with calcified aortic valve, AVA of 0.8 and gradient of 20mmHg. Compared to patient of AVA 0.8 and gradient of 40mmHg

A

List 2 ways these patients differ demographically
older age
female gender
concomitant presence of systemic arterial hypertension
2 ways they differ hemodynamically
Reduced LV compliance
Reduced stroke volume

A patient with low gradient AS will do ____ better/worse/equivalent with medical therapy. _____Better/worse/equivalent with surgery

20
Q

What is drug, half life, and time to wait before surgery

A

Prasugrel: Thienopyridines, P2Y12 ADP inhibitor, 4hr, 7d
Clopidogrel: Thienopyridines, P2Y12 ADP inhibitor, 8hr, 5d
Ticagrelor: Cyclopentyltriazolopyrimidine, P2Y12 ADP inhibitor, 12hr, 5d
Abciximab: Gp IIb/IIIa inhibitor, 30min, 12hr
Tirofiban: Gp IIb/IIIa inhibitor, 2.2hr, 2-4hr
Dabigatran: Direct thrombin inhibitor, 12hr, normal renal fct 2d, abnormal renal fct 4d