Premenstrual syndrome

Question 1

When do pts with PMS and premenstrual dysphoric disorder(PMDD) experience adverse physical, psychological, and behavioral symptoms?

Answer 1

luteal phase of the menstrual cycle

Question 2

What is the difference between PMS and PMDD?

Answer 2

PMS is predominantly somatic symptoms, while PMDD is predominantly psychological symptoms that seriously impair usual daily functioning and personal relationships

Question 3

What is MOA of using contraceptive pills for PMS?

Answer 3

suppressing the hypothalamic pituitary ovarian axis

Question 4

what is most likely to predict improvement in PMDD symptoms with oophorectomy?

Answer 4

resolution of PMDD symptoms with a GnRH agonist to initiate menopause like state

Question 5

What is the last resort for treatment for PMDD?

Answer 5

Bilateral oophorectomy

Question 6

When should SSRIs for PMDD be taken?

Answer 6

can take every day or only during the luteal phase

Question 7

How does exercise decrease symptoms of PMS?

Answer 7

increases circulating endorphins in the brain, which are feel good hormones and act similarly to serotonin

Question 8

What are risk factors for PMS?

Answer 8

family history, obesity and poor diet, becomes increasingly common as women age through their 30s and can worsen

Question 9

What are risk factors for PMDD?

Answer 9

previous anxiety, depression or other mental health problems

Question 10

What are normal premenstrual symptoms that affect 80% of women?

Answer 10

cramping, bloating, mastalgia

Question 11

Typical symptoms of premenstrual changes are best treated with?

Answer 11

NSAIDs, nutritional supplements

Question 12

What mineral supplements have demonstrated improvement in both physical and emotional symptoms of PMS?

Answer 12

at least 1200mg of calcium; pyridoxine and vit E have shown some benefit as well