Pregnancy

Question 1

What are the 3 key events in the ovarian cycle.

Answer 1

follicular growth
ovulation
luteal function

Question 2

What hormone is involved in follicular growth?

Answer 2

oestradiol

Question 3

What hormone is involved in luteal function?

Answer 3

progesterone

Question 4

What drug is given for MODY?

Answer 4

glibenclamide

Question 5

Do hypo and hyperthyroidism cause anovulatory cycles?

Answer 5

yes

Question 6

What is important for neonatal developemt in thyroid disease?

Answer 6

maternal thyroxine

Question 7

Is there an increased demand on the thyroid during pregnancy?

Answer 7

yes

Question 8

What happens to plasma protein binding during pregnancy?

Answer 8

increases

Question 9

When should thyroxine dose be increased for a hypothyroid patient in pregnancy?

Answer 9

as soon as they know they are preg

Question 10

What are the risks of untreated hypothyroidism in preg?

Answer 10

increased abortion, preeclampsia, abruption, postpartum, haemorrhage, preterm labour

Question 11

What can hyperthyroidism cause?

Answer 11

infertility, spontaneous miscarriage, stillbirth, thyroid crisis in labour

Question 12

What is hyperthyroid management in preg?

Answer 12

wait and see
b blockers in early preg
low dose anti thyroid drugs (propylthiouracil 1st trimester, carbimazole 2/3rd trimester)

Question 13

How much should a woman in early pregnancy increase her thyroxine dose when she finds out she is preggerz?

Answer 13

50% by 20 weeks