Paediatrics in Endocrine Flashcards

1
Q

What is one of the most common chronic diseases seen in children?

A

Type 1 diabetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How many type 1 diabetic children present with DKA?

A

25%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the pH in diabetic ketoacidosis?

A

<7.3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the symptoms of DKA?

A

comiting, abdo pain, altered consciousness, acidotic breathing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the commonest symptom of new diabetes in children?

A

polyuria, nocturnal enuresis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is secondary/tertiary thyroid disease usually associated with?

A

hypopituitarism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the clinical symptoms of congenital thyroid disease?

A

delayed jaundice
poor feeding but normal weight gain
hypotonia (decreased muscle tone)
skin and hair changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What tests for congenital thyroid disease and when is this done?

A

Guthrie test, day 5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What does Guthrie test measure?

A

TSH or T4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What does absence of thyroxine after 3 months of age lead to?

A

permanent developmental delay (cretinism)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Can hypothyroidism delay puberty?

A

Yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the treatment for children with hypothyroidism?

A

thyroxine replacement for life

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Is hyperthyroidism common in the young?

A

NO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What general symptoms may occur with hyperthyroidism in the young?

A

behavior problems, sleep disturbance, eating difficulties

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What can hyperthyroidism cause to happen to puberty?

A

precocious puberty

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What crisis can congenital adrenal hyperplasia cause?

A

Addison crisis (low sodium, low BP, high K)

17
Q

What is and Addisons crisis?

A

absent cortisol and aldosterone

18
Q

What does an Addison crisis require?

A

urgent salt and cortisol therapy

19
Q

What can congenital adrenal hyperplasia also cause in terms of virilisation?

A

female - ambiguous genitialia

male - precocious puberty