Osteoporosis

Question 1

What is the ratio of women to men?

Answer 1

5:1

Question 2

What percentage of bone is trabecular?

Answer 2

20%

Question 3

Which diabetes type increases risk?

Answer 3

type 1

Question 4

What type of scans are used most widely to measure BMD?

Answer 4

DEXA scans

Question 5

What is the difference between T score and Z score?

Answer 5

T score: young female adult population mean

Z score: age matched female population mean

Question 6

Ostopenia definition in terms of SD from norm?

Answer 6

BMD >1 but <2.5

Question 7

Osteoporosis definition in terms of SD from norm?

Answer 7

BMD >2.5

Question 8

severe osteoporosis definition in terms of SD from norm??

Answer 8

BMD >2.5 WITH fragility fracture

Question 9

What dose of vitamin D supplement should be give to female over 65?

Answer 9

10ug

Question 10

What dose of vitamin D supplement should be give to female over 65, who is housebound and frail?

Answer 10

20ug

Question 11

How is zeledronic acid administered?

Answer 11

once year IV infusion for 3 years

Question 12

What is denosumab and what does it target?

Answer 12

Fully human monoclonal antibody that targets and binds with high affinity and specificity to RANKL (receptor activator of nuclear factor-kB ligand)

Question 13

What line of agent is strontium ranelate?

Answer 13

3rd line

Question 14

When is strontium ranelate contraindicated?

Answer 14

if history of Thromboembolic Disease, IHD, Peripheral Arterial Disease, Uncontrolled Hypertension

Question 15

What is teriparatide?

Answer 15

recombinant parathyroid hormone, once daily injection