Diabetes

Question 1

Is type 1 diabetes an immune disorder?

Answer 1

yes

Question 2

When is there a peak in type 1 presentation?

Answer 2

pre school and peri puberty

small peak in late 30s

Question 3

List the symptoms of diabetes mellitus.

Answer 3

thirst
polyuria
thrush
weakness/fatigue
blurred vision
infections
weight loss

Question 4

Give 3 useful discriminatory tests for diabetes.

Answer 4

GAD/anti-islet cell antibodies
Ketones
C-peptide

Question 5

What pancreatic diseases causeType 3 diabetes?

Answer 5

pancreatic disease eg recurrent pancreatitis, haemochromatosis, CF

Question 6

What endocrine diseases cause Type 3 diabetes?

Answer 6

Cushings, acromegaly, phaechromocytoma, glucagonoma

Question 7

What are the drug induced causes of Type 3 diabetes?

Answer 7

glucocorticoids
diuretics
b-blockers

Question 8

What genetic conditions can lead to Type 3 diabetes?

Answer 8

CF, myotonic dystrophy, Turner’s

Question 9

What should you look out for in monogenic diabetes?

Answer 9

strong family history
young onset
GAD Negative
C-peptide positive

Question 10

What is Type 4 diabetes?

Answer 10

gestational

Question 11

What are the two main types of complications from diabetes?

Answer 11

macro-vasular eg heart disease and stroke

microvascular eg retinopathy, nephropathy, neuropathy