Pregnancy Flashcards
limit caffeine intake to < ___ mg/day
200 mg/day
Folate reduces risk of ___ tubal defects
* ___ mcg daily
* ___ mg for higher risk patients
- neural
- 400-600 mcg
- 4 mg
Calcium dereases risk of maternal ___ loss, HTN, and ___
* ___ mg daily
- bone, preeclampsia
- 1000-1300 mg
Iron helps with blood ___
* ___ mg daily
- oxygenation
- 27-30 mg
vitamins are ideally started ___ months prior to conception
3 months
Vaccine recommendations
- inactivated flu before october
- Tdap between 27-36 weeks of pregnancy
- COVID-19
T or F: live vaccines can be given during pregnancy
FALSE
Dont give a pregnant person a live vaccine goofy
T or F: Clinicians should weight the benefits and risks or initiating or continuing opioids in a pregnant patient
True
Drugs that are teratogenic
- Warfarin
- Lisinopril
- Li
- alcohol
- methotrexate
- isotretinoin
- statins
Pregnancy PK
- ___ in rate of absorption
- ___ GI motility
- ___ Vd of hydrophilic drugs
- ___ protein binding
- ___ CYP2C19 activity
- ____ CYP3A4 activity
- ___ renal and hepatic blood flow
- ___ CrCl
- decreased
- decreased
- increased
- decreased
- decreased
- increased
- increased
- increased
Diabetes Management in Pregnancy
- Prefered Treatment: ___
- Avoid: ___ and ___
- check blood sugar ___ times daily
- fasting blood glucose shold be below ___ mg/dL
- insulin
- metormin and glyburide
- QID
- 95 mg/dL
Hypertension Management in Pregnancy
- Prefered Treatment (6)
- Avoid (2)
Prefered:
1. Labetalol
2. amlodipine
3. nifedipine
4. HCTZ
5. hydralazine
6. methyldopa
Avoid
* ACE inhibitors (lisinopril, ramipril)
* ARBs (valsartan, candesartan)
T or F: N/V usually ocurrs in the 3rd trimester
False: occurs in the first trimester
Drugs for N/V
- pyridoxine.
- doxylamine + pyridoxine
- meclizine, dimenhydrinate, diphenhydramine 4. Last line: ondansetron, metoclopramide
T of F: heart burn occurs in the first half of pregnancy
False; last half of pregnancy
Drugs of heartburn
- antacids (magnesium hydroxide, calcium caronate)
- sucralafate
- H2 antagonists and protin pump inhibitors
Drugs for constipation
- osmotic laxatives (polyethylene glycol and lactulose)
- stooll softeners (docusate)
- bulk laxatives (psyllium)
Treatment of Pain, Fever, and Headache in Pregnancy
- Acetaminophen
AVOID NSAIDs after 32 weeks
Treatment of Cough and Cold in Pregnancy
* Congestion: ___ (2nd/3rd trimester) or ___
* Rhinorrhea and sleeplessness: ___ or ___
- pseudoephedrine, nasal saline spray
- chlorpheniramine, diphenhydramine
Treatment of Urinary Tract Infections in Pregnancy
* 1st gen ___ (4)
* AVOID: ___
cephalosporins
1. Cephalexin
2. Nitrofurantoin
3. amoxicillin
4. ampicillin
AVOID: Fluoroquinolones (cipro/levoloxacin, tetracyclines, doxycyclines, SMZ/TMP
Treatment of Thromboembolism in Pregnancy
* ___ for at least 6 months
* AVOID: ___
- anticoagulant
- warfarin
preeclampsia definition:
spike in blood pressure above ___ mmHg plus ___ (300mg/dL)
- 140/90 mmHg
- proteinuria
eclampsia definition:
___ or coma
seizure
complications of preeclampsia and eclampsia
- premature birth
- low birthweight
- growth retardation
- death
preeclampsia prevention
* ___ 60-80 mg starting in late ___ trimester
aspirin, 1st
severe preeclampsia (4)
- hydralazine
- labetalol
- nitroprusside
- nifedipine
AVOID: ACE inhibitors/ARBs
seizure management medication
magnesium sulfate 4-6g IV bolus
what does HELLP syndrome stand for?
- Hemolysis
- Elevated Liver enzymes
- Low Platelet count
HELLP Syndrome treatment
- platelets
- corticosteroids
- monitoring diagnostic lab values
Treatment of Group B Strep in Pregnancy
(antibiotics)
- Penicillin G or Ampicillin
- PCN allergy (mild) - Cefazolin
- PCN allergy (severe) - Clindamycin and Vancomycin
preterm labor is anytime before ___ weeks
37 weeks
Prevention of Preterm Labor
* No history of preterm birth: progesterone ___ mg vaginal suppository
* History of preterm birth: progesterone ___ IM weekly
- 200 mg
- 250 mg
Premature Membrane Rupture
Definition: water breaks but no ___.
contractions
Premature Membrane Rupture Treatments (4)
- corticosteroids
- antibiotics
- tocolytics
- magnesium sulfate
Premature Membrane Rupture Treatments - Corticosteroids
Purpose: reduce the risk of ___ distress syndrome
* 2 examples
respiratory
* betamethasone
* dexamethasone
Premature Membrane Rupture Treatments - antibiotics
Purpose: Group ___ strep prophylaxis (if indicated)
* 3 examples
B
* Penicillin G
* Cefazolin
* Vancomycin
Premature Membrane Rupture Treatments - tocolytics
Purpose: inhibit uterine ___
* 4 examples
contractions
* nifedipine
* indomethacin
* terbutaline
* magnesium sulfate
Premature Membrane Rupture Treatments - magnesium sulfate
Purpose: fetal ___ protection
neutral
