Long-Term Control Medications in Asthma and COPD - LABA Flashcards
Arformoterol tartrate brand name
Brovana
Arformoterol tartrate dosage forms
nubulizer solution
Arformoterol tartrate dosing ages
adults
COPD ONLY
formoterol brand name
Perforomist
formoterol dosage form
nebulizer solution
formoterol dosing ages
adults
COPD only unless used in combination with ICS
indacaterol name brand
Arcapta Neohaler
indacaterol dosage form
Neohaler
indacaterol dosing ages
adults
COPD only
olodaterol brand name
Striverdi Respimat
olodaterol dosage form
Respimat
olodaterol dosing ages
adults
COPD ONLY
salmeterol brand name
Serevent
salmeterol dosage form
Diskus
salmeterol dosing ages
≥ 4-11 and adults
adverse effects
- tachycardia
- headache
- tremor
- hypokalemia
2 boxed warnings
- increased risk of asthma related death for all monotherapy LABA use
- increasing hospitalizations in pediatric and adolescent patients
should not be used alone for asthma management
clinical pearls
* prolonged ___ seen with intentional overdoses
* not for ___ symptoms
* may be helpful for ___ induced bronchospasm
* formoterol and indacaterol capsules should not be taken orally
- QT
- acute
- exercise
pediatric considerations
most children < 4 yo cannot provide sufficient inspiratory flow for adequate lung delivery with a DPI
how do LABAs work
↑ cAMP → bronchial smooth muscle relaxation and inhibit hypersensitivity mediators from mast cells (histamine and leukotrienes)