Macronutrition Flashcards

1
Q

excess carbohydrates are converted to (2)

A
  • glycogen
  • triacyglycerol
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2
Q

What is the major energy source for humans?

A

carbohydrates

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3
Q

1 gram of carbs is how many kcal?

A

4 kcal

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4
Q

simple carbs

monosaccharides

A
  • glucose
  • fructose
  • galactose
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5
Q

simple carbs

disaccharides

A
  • sucrose
  • lactose
  • maltose
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6
Q

complex carbs

polysaccharides
* many ___ linked together in chains
* ___ in animals, and ___ and ___ in plants

A
  • monosaccharides
  • glycogen, starch, fiber
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7
Q

What is the most important carbohydrate fuel for the body?

A

glucose

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8
Q

T or F: glucose rarely appears are a monosaccharide in food.

A

True

part of a disaccharide or starch

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9
Q

T or F: fructose causes a great rise in blood glucose but not blood lipids.

A

False; fructose increases blood lipids but not blood glucose

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10
Q

high fructose corn syrup is suggested to be the cause of increased ___ and ___

A

diabetes and obesity

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11
Q

Digestion of carbohydrates

α-Amylase
* ___ starch and glycogen to ___ and ___
* exists in ___ and ___ juice

A
  • hydrolyzes, maltose, maltotriose
  • saliva and pancreatic
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12
Q

enzymes on the ___ surface of the small intestine
1. maltase “___:” maltose and maltotriose → ___
2. sucrase: sucrose → ___ and ___
3. lactase: lactose → ___ and ___

A

luminal
* α-glycosidase, glucose
* glucose and fructose
* glucose and galactose

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13
Q

T or F: only monosaccharides are absorbed in the body

A

True

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14
Q

Bacterial contribution

  • Bacterial enzymes break down carbs that we cannot by metabolizing them ___.
  • Results on production of ___ fatty acids, lactate, ___, ___, and ___.
  • May cause ___ and abdominal discomfort.
A
  • anaerobically
  • short chain, H2, CH4, CO2
  • flatulence
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15
Q

The glycemic index measures how ___ individual foods with raise ___ level.
* ratio of the AUC of the ___ response curve to that of ___

A

quickly, blood glucose
* blood glucose response, glucose

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16
Q

Dietary Fibers

Cellulose and Hemicellulose
* found in ___ cereals, ___, and ___ wheat
* increase ___ bulk and decreases ___ transit time
* insoluble

A
  • unrefined, brand , whole
  • stool, intestinal
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17
Q

Dietary Fibers

Lignin
* found in the ___ parts of vegetables
* binds ___ and ___
* insoluble

A
  • woody
  • cholesterol and carcinogens
18
Q

Dietray Fibers

Pectin
* found in ___
* decreases rate of ___ uptake and decreaces serum ___
* soluble

A
  • fruits
  • sugar, cholesterol
19
Q

Lipids in Diet

  • efficient source of energy ___ kcal/g
  • carrier for ___ vitamins
  • ___ is greater than 90% of dietary fat
  • ___, cholesterol, ___ esters, and fatty acids are less that 10% dietary fat.
A
  • 9 kcal/g
  • fat soluble
  • triacylglycerol
  • phospholipids, cholesterol
20
Q

Essential fatty acids

ω-3 fatty acids
* __ acid (18:3) in ___ oils
* ___ acid (20:5) and ___ acid (22:6) in ___ oils

A
  • α-linolenic, vegetable
  • Eicosapentaenoic (EPA), docosahexaenoic (DHA), fish
21
Q

Essential fatty acids

ω-6 fatty acids
* ___ acid (18:2) in ___ oil
* ___ acid (20:4) in ___ and ___

A
  • linoleic, corn
  • arachidonic, meat and fish
22
Q

Essential fatty acids

  • used to synthesize ___
  • deficiency is rare in US
  • ratio of ω-3 to ω-6 fatty acids in the diet is important in regulating blood ___, blood ___, and ___ functions
A
  • eicosanoids
  • blood pressure, blood clotting, immune
23
Q

Trans fatty acids

  • unsaturated fatty acids found in nature have ___ double bonds
  • hydrogenation converts ___ fatty acids to ____ fatty acids and produces ___ fatty acids as byproducts
  • ___ fatty acids have a higher melting point that ___ configuration
  • trans fats raise blood ___ levels and increase the risk of ___ disease.
A
  • cis
  • unsaturated to saturated, trans
  • trans, cis
  • cholesterol, heart
24
Q

Digestion of Lipids

  • fat needs to be ___ for digestion
  • this is done by ___ acids
  • gastric and pancreatic ___ hydrolyze triacylglycerol to ___ and monoacylglyceryol
  • fatty acids act as ___
  • esterase hydrolyzes monoacylglycerol and ___ ester

lipid phase made into small droplets

A
  • solubilized
  • bile
  • lipases, fatty acids
  • surfactants
  • cholesterol
25
Q

Utilization of lipids

  • ___ delivers lipid to peripheral tissues directly
  • ___ uses fat as an energy source
  • ___ does not used fat
  • when starved, liver converts fatty acid to ___ which are the used by ___ and ___
A
  • chylomicron
  • muscle
  • brain
  • ketone bodies, brain, muscle
26
Q

Proteins in Diet

Excess protein is a source of energy
* eventually converted to triacylglycerol in ___ tissue
* makes up ___ body weight

A
  • adipose
  • 20%
27
Q

Nitrogen Balance

negative nitrogen balance - ___ dietary intake of protein, trauma or illness

positive nitrogen balance - growing children, ___ women, or adults recovering from illness

A
  • inadequate
  • pregnant
28
Q

T or F: essential amino acids are synthesized by the body in sufficient amounts

A

False; they are the ones that can’t be synthesized or cannot be made sufficiently

arginine, methionine, and phenylalanine

29
Q

what are conditionally essential amino acids

A

amino acids that cannot be made if an essential amino acid is not ingested

if phenylalanine is not ingested enough, tyrosine cannot be made

30
Q

Digestion of Proteins

Gastric digestion
* low pH of ___ denatures proteins
* ___ are stable and active at acidic pH; espartic protease

A
  • 2
  • pepsins
31
Q

Digestion of Proteins

Intestinal digestion - ___ at the luminal surface
* brush border at the luminal surface of ___ cells
* rich in ___
* produce free amino acids and di and tri___

A

peptidases
* epithelial
* peptidases
* peptides

32
Q

Digestion of Proteins.

Intestinal Digestion - ___ peptidases
* amino acid and peptide ___ systems
* intracellular ___ of di and tripeptides
* practically only ___ amino acids are realeased to blood.

A

intracellular
* transport
* hydrolysis
* free

33
Q

Celiac Disease

  • ___ intolerance
  • ___ disorder in genetically predisposed individuals
  • caused by ___ to gluten
  • major proteins contained in ___, ___ , and ___
  • lining of ___ is inflamed and damaged causing ___ , ___ , and ___
A
  • gluten
  • autoimmune
  • exposure
  • wheat, rye, and barley
  • small intestine, diarrhea, weight loss, and malnutrition
34
Q

Energy Reserves

  • excess energy is stored mostly as fat in ___ tissue
  • glycogen in the liver to maintain ___ levels
  • glycogen in muscle is used for ___
  • protein is not a ___ energy reserve
A
  • adipose
  • blood glucose
  • exercise
  • preferred
35
Q

Well-fed state

  • ___ release
  • glycolysis and ___ synthesis
  • catabolism of ___ acids
  • ___ acid synthesis
  • no ____ = no ___ cyclle
A
  • insulin
  • glycogen
  • amino
  • fatty
  • gluconeogenesis, Cori
36
Q

Early Fasting State

  • ___ release
  • ____ breakdown
  • gluconeogenesis: ___ cycle and ___ cycle
  • no ____ of amino acids
A
  • glucagon
  • glycogen
  • Cori, Alanine
  • catabolism
37
Q

Fasting State

  • ___ release
  • gluconeogenesis
  • protein is used as a major carbon and ___ source (2 amino acids)
  • ___ in adipose tissue
  • fatty acid ___
  • ketogenesis
  • reduced ___ hormones
  • daily basal energy requirement drops by ___%
A
  • glucagon
  • nitrogen (alanine, glutamine)
  • lipolysis
  • oxidation
  • thyroid
  • 25%
38
Q

Caloric Homeostasis

  • if [glucose] < ___ nM (27 mg/dL), coma and death with follow
  • hyperglycemia leads to ___ , ___ coma, and complications of ___
A
  • 1.5 nM
  • dehydration, hyperglycemic, diabetes
39
Q

Energy for Brain

  • brain uses more than ___% of total energy
  • ___ g of glucose/day is preferred
  • uses ___% of total oxygen
  • membrane potential uses ___ ATPase
  • brain does not use ___ or ___ storage
  • use ketone bodies during starvation made from ___ in the liver
A
  • 20%
  • 100-120g
  • 15-20%
  • Na+/K+
  • fat, glycogen
  • acetyl-CoA
40
Q

Protein-energy malnutrition

Marasmus: inadequate intake of both ___ and ___
* thin, wasted appearance

A

protein and energy

41
Q

Protein-energy malnutrition

Kwashiorkor: inadequate intake of ___ with adequate ___ intake
* mainly in children ___ years of age
* deceptice plump appearance due to ___

A

protein, energy
* 1-3
* edema