PPT 01 and 02 (Respiratory) Flashcards
lined primarily by ciliated epithelium and goblet cells
conducting system
consists of alveoli that are lined by epithelial type I (membranous) and type II pneumonocytes
exchange system
a nasal flora that may cause shipping fever
Mannheimia haemolytica
a nasal flora that is responsible for atrophic rhinitis
bordetella bronchiseptica
nasal flora are not present in these regions
distal portion of respiratory system (bronchi, bronchioles, alveoli)
non specific defense mechanisms
air turbulences, mucus trapping, mucociliary clearance, phagocytosis, coughing, sneezing
defense mechanisms of conducting system
air turbulences, centrifugal forces, particle impaction, mucus entrapment, mucociliary clearance, IgA
first line of defense created by nasal turbinates
air turbulence and centrifugal forces
particle size that can enter the nasal cavity
greater than 10 micometer
particle size that can enter alveoli
less than 2 micrometer
present in bronchial bifurcations that help produce immune cells
bronchial-associated lymphoid tissue
main effector cell in the inflammatory process of the lung through production of cytokines
pulmonary alveolar macrophage
medical term that describes a nose bleed
epistaxis
coughing up blood or presence of blood in mouth, saliva or sputum
hemoptysis
frequent indicator of nasal trauma or nasal neoplasia
epistaxis
In cattle, epistaxis-hemoptysis is often associated with?
ruptured pulmonary vessel (aneurysm)
In horses, epistaxis is also seen in?
exercise induces pulmonary hemorrhage and ethmoid hematoma
an important condition in older horses clinically characterized by chronic, progressive and generally unilateral nasal bleeding
ethmoid hematoma
Nasal congestion or nasal hemorrhage is commonly seen following exposure to irritant gases such as
ammonia, hydrogen sulfide, nitrogen dioxide
steps of cell injury, degeneration and repair
Cell injury, degeneration, detachment, exfoliation, inflammation, mitosis, repair
injury and repair of nasal mucosa takes how many days
14 days
lungs can be exposed to bacterial aerosols but within how many hours will all bacteria be destroyed and removed from the lung
24 hours
appears as a single, pedunculated tumor-like, soft mass arising from ethmoid conchae
ethmoid hematoma
factors that reduce the pulmonary defense mechanism and predispose the lung ot secondary bacterial pneumonia
virus, stress, dehydration, lung edema, uremia, ammonia, and immunodeficiency
Nasal congestion and hyperemia are frequently seen in?
bloat, toxemia, sepsis, rhinitis
nasal hemorrhages are common in?
domestic animals
Common causes of epistaxis in horses
ethmoid hematoma, exercise induced pulmonary hemorrhage
In all species nasal tumors and rhinitis are also causes of
epistaxis
implications of purulent rhinitis
pyogenic organisms
mucus secretions due to goblet cell hyperplasis and indicates chronic irriration to moderate injury
catarrhal exudate
rhinitis which is due to severe injury to mucosa
fibrinous
rhinitis with accumulation of macrophages, lymphocytes, plasma cells and CT
granulomatous
an important equine disease that may occur as an outbreak with high morbidity
strangles
causative agents of strangles
Streptococcus equi
Strangles involvement of retro pharyngeal lymph nodes can
compress laryngeal nerves and cause secondary
laryngeal hemiplegia
strangles that metastasis to internal organs
bastards strangles
most common organisms that cause secondary bacterial rhinitis resulting to mucopurulent rhinitis in dogs
bordetella bronchiseptica, E. coli, Streptococci, Staphylococci
viruses causing canine upper respiratory infections
Canine distemper, Canine adenovirus, canine infectious parainfluenza
Viral rhinitis are generally acute and transient and can cause a highly contagious condition referred to as
kennel cough
virus, chlamydia and mycotic organisms causing rhinitis and conjuctivitis in cats
feline calicivirus, feline infectious rhinotracheitis, chlamydiophila pssitaci, cryptococcus neoformans
organisms that cause feline rhinitis-sinusitis-conjuctivitis
FHV-1, Feline calicivirus, Chlamydophila pssitaci
Granulomatous rhinitis is typically associated to organisms that survive phagocytosis such aa
Mycobacterium spp, Crytococcus, Blastomyces
a protist that can cause multilobulated granuloma
Rhinosporidium seeberi
a disease caused by Herpes virus in piglets less than 2 weeks old
Inclusion body rhinitis
sequels to rhinitis
sinusitis, meningitis and encephalitis, otitis, guttural pouch empyema, lymphadenitis
accumulation of mucus
mucocele
sinusitis in cattle can be caused by?
improper dehorning
accumulation of mucus in guttural pouch
guttural pouch mucocele
accumulation of pus in guttural pouch due to pyogenic organisms
guttural pouch empyema
Other common abnormalities of guttural pouches that is characterized by an abnormal accumulation of air
tympani
Clinical signs of guttural pouch empyema
intermittent nasal discharge, enlargement of retro pharyngeal lymph nodes, and parotid swelling
sequels to guttural pouch mycosis
epistaxis, thromboembolism with ataxia, blindness, injury to cranial nerves
clinical signs of rhinitis and sinusitis
sneezing, wheezing, stertos, nasal discharge, unilateral or bilateral
common affected by nasal tumors
dogs and cats
epithelial tumors of nasal passages
adenoma, carcinoma
nasal tumors can result to
craniofacial deformation, exophthalmia, metastasis
most common nasal stromal tumors
fibrosarcoma, osteocarcoma, chondrosarcoma
most common nasal epithelial tumors
carcinoma, adenocarcinoma, undifferentiated carcinoma
signs and diagnosis of nasal tumors
persistent nasal discharge, epistaxis, airflow obstruction, facial deformity, exophthalmia, neurological signs
causative agent of necrotic laryngitis or calf diphtheria as a result of secondary infection
Fusobacterium necrophorum
fusobacterium necrophorum in pigs are restricted in the oral mucosa and referred to as?
oral necrobacillosis
there are presence of plaques of purulent exudate on the surface of the tracheal mucosa
suppurative tracheitis
suppurative tracheitis are seen in what virus infection of cattle
IBR,BRSV, PI-3
a metastrongyle nematode found worldwide that generally affects young dogs
Oslerus osleri
organism causing verminous pneumonia in bovines
Dictyocaulus viviparus
organism causing verminous pneumonia in ovine
dictyocaulus filariae
organism causing verminous pneumonia in porcine
metastrongylus apri
organism causing verminous pneumonia in foxes and dogs
cronosoma vulpis
other terms for parasitic bronchitis
verminous pneumonia or verminous bronchitis
typically implies severe mucosal injury with leakage of fibrinogen from blood vessels.
fibrinous rhinitis
primary causes of rhinitis in cats
Feline calicivirus, Feline Infectious Rhinotracheitis, Chlamydophila spp and Cryptococcus neoformans
common secondary pathogens in feline rhinitis.
Bordetella bronchiseptica, E. coli and Streptococcus spp
causes rhinitis, lymphadenitis and guttural pouch empyema in horses
Strangles
cause nasty sequels such as sinusitis, meningitis, lymphadenitis in all species, and guttural pouch empyema in horses
rhinitis
transient infection of young piglets caused by herpesCytomegalovirus
Inclusion body rhinitis
world wide disease characterized by inflammation and atrophy of the nasal turbinates
atrophic rhinitis
etiologies of atrophic rhinitis
Pasteurella multocida and Bordetella bronchiseptica
accumulation of mucus in sinuses
sinus mucocele
purulent exudate in sinuses
sinus empyema
ventral dilations of the auditory (Eustachian) tubes in horses
guttural pouches
e most common guttural pouch problems
emypema, mucocele, tympany, mycosis, hemorrhage
often produce nasal discharge mimicking rhinitis or may induce exophthalmia or craniofacial deformation
nasal tumors
fibrinonecrotic inflammation of the larynx that in some cases results in airway obstruction, aspiration of exudate into the lungs and only rarely in septicemia known as fusobacteremia
Necrotic laryngitis or Calf diphtheria
parasitic disease of dogs and other carnivores characterized by the presence of large nodules in the tracheobronchial bifurcation
Oslerus osleri