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ZZ3 Systemic Pathology > bones and joint > Flashcards

bones and joint Flashcards

1
Q

bones with direct synthesis of bone matrix by osteoblast

A

skull, mandible, clavicle

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2
Q

the formation of weight bearing bone

A

endochondral osteogenesis

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3
Q

produces and mineralizes a matrix

A

osteoblast

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4
Q

present on surface of lamellar bone

A

osteoid

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5
Q

formed by enclosure of osteoblast within osteoblast which functions in demineralization remineralization in maintaining calcium homeostasis

A

osteocyte

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6
Q

osteocyte is regulated by

A

PTH and Vit D

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7
Q

where is osteoclast located

A

howships lacunae

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8
Q

derived from mononuclear phagocytes within the marrow

A

osteoclast

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9
Q

common in chondrodystrophic breeds such as dachshund

A

intervertebral disk disease

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10
Q

characterized by focal erosion and fibrillation of articular cartilage

A

degenerative joint disease

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11
Q

responsible for the bulk of bone removal or osteoclasis

A

osteoclasts

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12
Q

abnormal dorsal curvature of the spine

A

kyphosis

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13
Q

lateral deviation or curvature of the spine

A

scoliosis

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14
Q

abnormal ventral curvature of the spine

A

Lordosis

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15
Q

abnormal dorsal and lateral curvature of the spine

A

kyphoscoliosis

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16
Q

fusion of adjacent limbs

A

syndactyly

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17
Q

osseous union of bones that are normally distinct

A

synostosis

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18
Q

hypoplasia of limbs, hands, and feet, attached directly to the body

A

phocomelia

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19
Q

absence of limb or limbs

A

amelia

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20
Q

excess in the number of limbs

A

polymelia

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21
Q

absence of longitudinal segment of a limb

A

hemimelia

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22
Q

clinical disease of bone pain and fracture characterized microscopically by a reduction of bone mass

A

osteoporosis

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23
Q

very dense bone with no medullary cavity but are susceptible to fracture

A

osteopetrosis

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24
Q

refers to a usually nodular, benign bony growth projecting outward from a surface of bone

A

exostosis

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25
a bony growth within the medullary cavity
enostosis
26
fibrovascular and histiocytic tissue arising from insertion of synovial membrane and spreads over adjacent cartilage as velvety membrane
pannus
27
unorganized meshwork of woven bone that forms a following fracture
callus
28
chondrodysplasia is also known as
disproportionate dwarfism
29
In chondrodysplasia, which growth of the bone is abnormal
endochondral growth
30
chondrodysplastic bovines are also referred to as
bull dog calves
31
genetic defect which osteoclasts fail to reabsorb the primary spongiosa
osteopetrosis
32
osteopetrosis lesions are sporadically seen in bones of stillborn calves infected with this virus
BVD
33
osteopetrosis is rarely seen in these species
dogs and cats
34
a small sized calf has large head with shortened cranial base and prominent eyes, pendulous abdomen, shorth thick legs is known to have this abnormality
chondrodysplasia
35
disease in poultry which may also affect osteoclasts leading to osteopetrosis
avian leucosis
36
genetic disease of pigs characterized by abnormal deposition of bone along the periosteal surface of long bones
porcine hyperostosis
37
notable characteristics of porcine hyperostosis
swelling of the forelegs
38
a teratogenic substance taken by pregnant women resulting to phocomelia babies
Thalidomide
39
distal portion of the limb is missing
peromelia
40
fusion of the toes common in pigs
syndactyly
41
in syndactylia, which feet is commonly affected
forefeet
42
increase number of digits
polydactylia
43
which hormone decrease bone resorption and stimulate new bone formation
calcitonin
44
which hormone increase bone resorption
PTH
45
which substance faciliate absorption of calcium from intestine and a synergistic with PTH
Vit D
46
maintain basic shape while bone is growing
modeling
47
integration of continuous endochondral ossification
modeling
48
mature skeleton renews itself
remodeling
49
more rapid than haversian bone remodeling
trabecular bone remodeling
50
hormone which inhibit osteoclasia
estrogen
51
once removed, it increases internal remodeling
estrogen
52
increases osteoclasia
PTH
53
decrease bone resorption and osteoclasis
calcitonin
54
remodeling decreases due to
age
55
too little bone
osteopenia
56
increases bone resorption and reduces mineralization of osteoid
PTH
57
decrease phosphorus reabsorption in kidneys
PTH
58
reduces bone resorption and stimulate new bone formation
calcitonin
59
Vit D plant origin
ergocalciferol
60
animal origin of vit d
cholecalciferol
61
principally utilize vit d3
poultry
62
facilitate absorption ofcalcium from intestine
vit d
63
growth plate become narrow and metaphyseal face sealed by layer of bone
arrest line or harris line
64
impairment of osteoclastic activity within the primary trabeculae
growth retardation lattice
65
alteration in shape or structure of previously normally formed part usually arise late in fetal life
deformity
66
structural defects due to localized error in embryonic period
malformation
67
too little formation of matrix osteoblast insufficiency
osteoporosis
68
immature osteopenia
ricket
69
mature osteopenia
osteomalacia
70
too much bone
osteopetrosis
71
decreased formation of osteoid
osteoporosis
72
inadequate mineralization in young growing animals
rickets
73
adult form of rickets
osteomalacia
74
etiology of fibrous osteodystrophy
hyperparathyroidism
75
separation of bone fragment with its tendon or ligament
avulsion
76
bone shattered into several small fragments
comminuted
77
inflam of bone
osteitis
78
inflam of bone and bone marrow
osteomyelitis
79
inflamof periosteum
periostitis
80
cause non suppurative osteomyelitis but granulomatous
brucella suis
81
etiology of lumpy jaw
actinomyces bovis
82
cause osteomyelitis of lumber vertebral epiphysis and adjacent discs or diskospondylitis
Brucella suis
83
fibrovascular tissue arising synovium and covering the articular surface such that in rheumatoid arthritis
pannus
84
altered acid mucopolysaccharides produced by surface cells of articular cartilage loss of elasticity
degenerative joint disease
85
macroscopic particular matter in synovial space or bone in cartilage fragment
joint mice
86
wobbler syndrome
cervicospinal arthropathy
87
nucleus pulposus losses semisolid nature and plasticity, become more cartilage like
invertertebral disk disease
88
formation and ultimate fusion of osteophytes on ventral aspect of adjacent vertebral bodies
spondylosis
89
cause arthritis in swine and sheep
Erysipelothrix rhusiopathiae
90
cause infectious arthritis that may cause meningitis
Streptococcus suis
91
cause infectious arthritis which may also affect the lungs
haemophilus parasuis
92
In LM, macrophage and foreign body giant cell in conjunction with clusters of sharp crystal
gout
93
crystallic material with needle shaped crystal
pseudogout
94
direct synthesis of bone matrix by osteoblast
intramembranous osteogenesis
95
develops from a cartilaginous model
endochondral osteogenesis
96
chondroid core resorbed fusion and enlargment to form lamellar bone
secondary spongiosa
97
thin membrane attached to underlying bone
periosteum
98
anabolic process
apposition
99
catabolic processes
resorption

ZZ3 Systemic Pathology (16 decks)

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