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Haematology > Polycythameia Vera > Flashcards

Polycythameia Vera Flashcards

1
Q

What is polycythaemia vera?

A

Neoplastic proliferation of RBCs

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2
Q

What are risk factors for polycythaemia vera?

A

Age (older)

Male

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3
Q

What are the clinical features of polycythaemia vera?

A 
Headache 
Blurry vision 
Flushed appearance
Palmar erythema 
Itching after bath
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4
Q

What causes the features of polycythaemia vera?

A

Hyper viscosity of blood

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5
Q

What investigations are done in suspected polycythaemia vera?

A

FBC

EPO

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6
Q

What does the FBC show in polycythaemia vera?

A

Raised HB

Raised haematocrit

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7
Q

What does EPO show in polycythaemia vera?

A

Low

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8
Q

How is polycythaemia vera managed?

A

Phlebotomy

Aspirin

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9
Q

What is the aim for haematocrit in polycythaemia vera?

A

< 45%

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10
Q

What mutation is related to polycythaemia vera?

A

JAK2 mutation

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Haematology (28 decks)

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