Essential Thrombocytosis Flashcards
1
Q
What is essential thrombocytosis?
A
Neoplastic proliferation of megakaryocytes
2
Q
What investigations are done for suspected essential thrombocytosis?
A
FBC
Bone marrow biopsy
3
Q
What does the FBC show in essential thrombocytosis?
A
Thrombocytosis
- platelets >600 x 10^9
4
Q
What does the bone marrow biopsy show in essential thrombocytosis?
A
Increased megakaryocytes
5
Q
How is essential thrombocytosis managed?
A
Antiplatelet
Hydroxycarbamide
6
Q
What are features of essential thrombocytosis?
A
Headache
Atypical chest pain
Thrombosis + microvascular occlusion