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Haematology > Liver Function Tests > Flashcards

Liver Function Tests Flashcards

1
Q

What is included in the LFTs?

A 
Bilirubin 
ALT 
AST 
ALP 
Albumin 
Total protein
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2
Q

What is the normal bilirubin level?

A

3-17 umol/L

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3
Q

What can cause a raised bilirubin?

A

Liver pathology

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4
Q

What can cause a raised unconjugated bilirubin?

A

Increased breakdown of RBCs

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5
Q

What can cause a raised conjugated bilirubin?

A

Hepatitis
Cirrhosis
Bile duct blockage

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6
Q

What does ALT stand for?

A

Alanine aminotransferase

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7
Q

What is the normal level of ALT?

A

3-40 iu/L

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8
Q

What can cause a raised ALT?

A

Very high = viral hepatitis

Chronic hepatitis
High alcohol intake
Diabetes
Raised serum triglycerides

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9
Q

What does AST stand for?

A

Aspartate aminotransferase

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10
Q

What is the normal level of AST?

A

3-30 iu/L

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11
Q

What can cause a raised AST?

A

Very high = viral hepatitis

Chronic hepatitis
Alcohol abuse

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12
Q

What does ALP stand for?

A

Alkaline phosphatase

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13
Q

What is the normal level of ALP?

A

30-100 umol/L

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14
Q

What can cause a raised ALP?

A

Bile duct blockage

Paget’s disease
Osteomalacia
Vit D deficiency

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15
Q

What is the normal albumin level?

A

35-50g/L

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16
Q

What can cause a low albumin level?

A

Liver disease

Shock
Severe inflammation

Kidney disease

17
Q

What can cause a high albumin level?

A

Dehydration

18
Q

What is the normal level of total protein?

A

60-80 g/L

19
Q

What can cause a low total protein level?

A

Liver disorder
Kidney disorder
Protein absorption problem

20
Q

What can cause a high total protein level?

A

Dehydration

Accumulation of abnormal protein

21
Q

What other test can be added to the LFTs?

A

GGT

22
Q

What goes GGT stand for?

A

Gamma glutamyl transferase

23
Q

What is the normal level of GGT?

A

8-60 u/L

24
Q

What can cause a high GGT?

A

Liver disease

Alcohol abuse
NSAID use
Other drugs

25
Q

What can cause a low GGT?

A

COCP

Haematology (28 decks)

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