Poisoning Flashcards

1
Q

What are the most important steps in management of someone who comes in with a poisoning or overdose

A

ABCs
Consider second poison
Call poison control

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2
Q

What is the coma cocktail

A

Dextrose-50 mL of D50W (or glucagon 1mg IM)
Oxygen
Narcan (2 mg, if not life threatening can give 0.1 mg and double every 2 minutes up to 10 mg)
Thiamine (100 mg but make sure to give with the dextrose

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3
Q

List five important questions to ask on history

A
When was it taken 
How much was taken 
What else was taken 
How was it taken 
Why was it taken
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4
Q

What did someone take and what should you give them:

Tachycaric, enlarged pupils, sweating

A

They took a stimulant (cocaine, amphetamine, ecstacy

No antidoe
Can give Benzos

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5
Q

What did someone take and what should you give them:

Tachy, enlarged pupils, dehydrated, high temp, red

A

They took an anticholinergic (antipsyphotics, tricyclics)
Give Physostigmine
Give Bicarb in TCA overdose

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6
Q

What did someone take and what should you give them:

Normal vitals, pinpoint pupils, Sweating, drooling, tearing, diarrhea, emesis

A

They took a cholinergic
Mushrooms
Organophosphates
Insecticides

Give atropine

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7
Q

What did someone take and what should you give them:

Bradycardic, pin point pupils, low resp rate

A

Opioids

Give naloxone

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8
Q

What did someone take and what should you give them:

Bradycardic , lethargic

A

Sedative-hypnotic
Anti epileptics, barbituates, muscle relaxants
Supportive care

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9
Q

What did someone take and what should you give them:

Normal vitals but very lethargic

A
Benzoz 
Give flumazenil (watch for swizures) 
May need to intubate \

Unlikely able to give a GI decontamination due to risk of aspiration due to lethargy

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10
Q

What did someone take and what should you give them:

Low heart rate as only symptom

A

Beta blocker
Give glucagon and calcium channel agonists or calcium chloride

Consider atropine, vasopressor, insulin and glucose

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11
Q

A kiddo got into her moms iron because she thought it looked like candy
What do you give

A

Deferoxamine

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12
Q

When do you give gastric lavage

A
  1. Lethal dose
  2. NO known antidote
  3. Taken with in 2 hours
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13
Q

When do you use continuous bowel irrigation

A

SR/Long acting drug

Packers

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14
Q

When to use activated charcoal

A
  1. Within 1-2 hours
  2. Able to be bound by the charcoal

Unable to use AC

  1. Caustic acids and alkalis
  2. Alcohol
  3. Lithium
  4. Heavy metals
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15
Q

What labs would you get

A
CBC lytes, creat 
Osolarity 
Osmolar gap 
Quantitave drug levesl (tylenol, salicylates, ethanol, iron, lithium, digoxin etc) 
Pregnancy test 
ECG
CVR (aspiration and pulmonary edema)
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16
Q

What labs to get in Acetaminophen oversode

A

CBC
LYtes
Creat
LFTS

Acetaminophen level

Then use normogram to see if you need to treat with NAC

17
Q

What is the toxic dose of tylenol

A

150 mg/kg

18
Q

When can you measure acetaminophen levels after ingestion to use the normogram

A

4 hours technically

Before then can give activated charcoal unless unable to protect airway

19
Q

When can you give N Acetylcysteine

A

Over normogram and known time of ingestion
If time of ingestion not known, >24 hours, or chronic use, can give if Acetaminophen high on blood work or abnormal LFTs
Give if any abnormal LFTs
(try to give before LFTs abnormal

20
Q

When do you stop NAC

A

When Acetaminophen <10 AND LFTs normal

21
Q

Signs of asa overdose

A

Tinnitus, tachypnea, resp alkalosis and then metabolic acidosis

22
Q

How to treat ASA overdose

A
Bicarb 
Monitor for hypokalemia 
Glucose 
Dialysis 
Consider Activated charcoal 

Try to avoid intubation-Resp need to account for metabolic Acidosis

23
Q

Signs of a methanol overdose and how to treat

A

Metabolic acidosis with osmolal gap
Blindness

Fomepazole, bicarb, hemodialysis

24
Q

What is the titration goal for naloxone

A

RR 12

Not Level of consciousness

25
Q

List three safety points for drugs in the home with children

A

Keep out of reach
Keep in child safe containers
Don’t take in view of children
Don’t call the medicine candy