Plasmodium Flashcards
[6] Stages of Development of Plasmodium Spp.
- Ring forms
- Developing/ Growing Trophozoites
- Immature/Presegmenting Schizonts
- Mature Schizonts
- Microgametocytes
6.Macrogametocytes
early trophozoites.
[stages of development of plasmodium spp]
Ring forms
As the name implies, refers to a ring like appearance of the malarial parasite following invasion into a previously healthy RBC.
[stages of development of plasmodium spp]
Ring forms
Space inside the ring is known as a vacuole.
[stages of development of plasmodium spp]
Ring forms
Remnants of the cytoplasmic circle and chromatin dot are still intact until late development.
[stages of development of plasmodium spp]
Developing trophozoites
The parasite is actively growing during this stage, the amount of RBC space invaded is significantly more than that of the ring form.
[stages of development of plasmodium spp]
Developing trophozoites
Active chromatin replication is seen.
[stages of development of plasmodium spp]
Immature schizonts
Expands and occupies more space within the RBC.
[stages of development of plasmodium spp]
Immature Schizonts
Merozoites: emergence of the fully developed stage of the asexual sprozoa trophozoite.
[stages of development of plasmodium spp]
Mature schizonts
Typical microgametocyte is roundish in shape (except P. falciparum, which is crescent-shaped)
[stages of development of plasmodium spp]
Microgametocytes
Large diffuse chromatin mass that stains pink to purple and is surrounded by a colorless to pale halo.
[stages of development of plasmodium spp]
Microgametocytes
pigment is usually visible.
[stages of development of plasmodium spp]
Microgametocytes
Round to oval (except P. falciparum, which is crescent shaped)
[stages of development of plasmodium spp]
Macrogametocytes
Pigment is also present, and its color and distribution in this morphologic form vary by individual Plasmodium species.
Macrogametocytes
Disease: malignant malaria, aestivo-autumnal, falciparum malaria, subtertian malaria, pernicious malaria, Black water fever malaria.
[Plasmodium spp.]
Plasmodium Falciparum
It is most prevalent in the tropics and subtropics.
[Plasmodium spp.]
Plasmodium Falciparum
It causes the most severe form of malaria.
[Plasmodium spp.]
Plasmodium Falciparum
It still remains almost unchallenged as the greatest killer of the human race over most parts of Africa and elsewhere in the tropics.
[Plasmodium spp.]
Plasmodium Falciparum
Maurer’s dots occasionally seen.
[Plasmodium spp.]
Plasmodium Falciparum
Pigment: BLACK, coarse and conspicuous in parasite.
[Plasmodium spp.]
Plasmodium Falciparum
Number of merozoites: 6-32, average is 20-24
[Plasmodium spp.]
Plasmodium Falciparum
Schizonts: bad prognosis
[Plasmodium spp.]
Plasmodium Falciparum
Stages found in Circulating Blood: Young, growing trophozoites (ring forms) and gametocytes.
[Plasmodium spp.]
Plasmodium Falciparum
Young rings are small, delicate, often with double chromatin dots, accole, applique.
[Plasmodium spp.]
Plasmodium Falciparum