Plasmodium Flashcards
[6] Stages of Development of Plasmodium Spp.
- Ring forms
- Developing/ Growing Trophozoites
- Immature/Presegmenting Schizonts
- Mature Schizonts
- Microgametocytes
6.Macrogametocytes
early trophozoites.
[stages of development of plasmodium spp]
Ring forms
As the name implies, refers to a ring like appearance of the malarial parasite following invasion into a previously healthy RBC.
[stages of development of plasmodium spp]
Ring forms
Space inside the ring is known as a vacuole.
[stages of development of plasmodium spp]
Ring forms
Remnants of the cytoplasmic circle and chromatin dot are still intact until late development.
[stages of development of plasmodium spp]
Developing trophozoites
The parasite is actively growing during this stage, the amount of RBC space invaded is significantly more than that of the ring form.
[stages of development of plasmodium spp]
Developing trophozoites
Active chromatin replication is seen.
[stages of development of plasmodium spp]
Immature schizonts
Expands and occupies more space within the RBC.
[stages of development of plasmodium spp]
Immature Schizonts
Merozoites: emergence of the fully developed stage of the asexual sprozoa trophozoite.
[stages of development of plasmodium spp]
Mature schizonts
Typical microgametocyte is roundish in shape (except P. falciparum, which is crescent-shaped)
[stages of development of plasmodium spp]
Microgametocytes
Large diffuse chromatin mass that stains pink to purple and is surrounded by a colorless to pale halo.
[stages of development of plasmodium spp]
Microgametocytes
pigment is usually visible.
[stages of development of plasmodium spp]
Microgametocytes
Round to oval (except P. falciparum, which is crescent shaped)
[stages of development of plasmodium spp]
Macrogametocytes
Pigment is also present, and its color and distribution in this morphologic form vary by individual Plasmodium species.
Macrogametocytes
Disease: malignant malaria, aestivo-autumnal, falciparum malaria, subtertian malaria, pernicious malaria, Black water fever malaria.
[Plasmodium spp.]
Plasmodium Falciparum
It is most prevalent in the tropics and subtropics.
[Plasmodium spp.]
Plasmodium Falciparum
It causes the most severe form of malaria.
[Plasmodium spp.]
Plasmodium Falciparum
It still remains almost unchallenged as the greatest killer of the human race over most parts of Africa and elsewhere in the tropics.
[Plasmodium spp.]
Plasmodium Falciparum
Maurer’s dots occasionally seen.
[Plasmodium spp.]
Plasmodium Falciparum
Pigment: BLACK, coarse and conspicuous in parasite.
[Plasmodium spp.]
Plasmodium Falciparum
Number of merozoites: 6-32, average is 20-24
[Plasmodium spp.]
Plasmodium Falciparum
Schizonts: bad prognosis
[Plasmodium spp.]
Plasmodium Falciparum
Stages found in Circulating Blood: Young, growing trophozoites (ring forms) and gametocytes.
[Plasmodium spp.]
Plasmodium Falciparum
Young rings are small, delicate, often with double chromatin dots, accole, applique.
[Plasmodium spp.]
Plasmodium Falciparum
Disease: vivax malaria or benign tertian malaria.
[Plasmodium spp.]
Plasmodium Vivax
Most widespread, found in most endemic areas including some temperate zones.
[Plasmodium spp.]
Plasmodium Vivax
It is more common in temperate than in tropical region.
[Plasmodium spp.]
Plasmodium Vivax
It is the second common Malaria in the Philippines.
[Plasmodium spp.]
Plasmodium Vivax
Ring forms occupies 1/3 diameter of RBC.
[Plasmodium spp.]
Plasmodium Vivax
Schuffner’s dots present in all stages except early young forms.
[Plasmodium spp.]
Plasmodium Vivax
Irregular, ameboid trophozoites, has spread out appearance.
[Plasmodium spp.]
Plasmodium Vivax
Pigment: GOLDEN BROWN, inconspicuous
[Plasmodium spp.]
Plasmodium Vivax
Number of merozoites: 12-24, average is 16
[Plasmodium spp.]
Plasmodium Vivax
Disease: malariae or quartan malaria
[Plasmodium spp.]
Plasmodium Malariae
Similar range as P. falciparum, but less common and patchy distribution.
[Plasmodium spp.]
Plasmodium Malariae
Common in tropical Africa, Burma, Sri lanka, India, Malaysia and Indonesia.
[Plasmodium spp.]
Plasmodium Malariae
It is occasionally seen in the Philippines.
[Plasmodium spp.]
Plasmodium Malariae
Ziemann’s dots rarely seen.
[Plasmodium spp.]
Plasmodium Malariae
Rounded, compact trophozoites with dense cytoplasm.
[Plasmodium spp.]
Plasmodium Malariae
Band form trophozoites occasionally seen.
[Plasmodium spp.]
Plasmodium Malariae
Pigment: DARK BROWN, conspicuous
[Plasmodium spp.]
Plasmodium Malariae
Plasmodium Ovale
Rosette schizonts occasionally seen.
[Plasmodium spp.]
Plasmodium Malariae
No. of merozoites: 6-12, average is 8.
[Plasmodium spp.]
Plasmodium Malariae
Disease: ovale malaria, Benign tertian malaria.
[Plasmodium spp.]
Plasmodium Ovale
It is the least common Plasmodium infecting man.
[Plasmodium spp.]
Plasmodium Ovale
It occurs mostly in tropical Africa, principally on the west coast and is endemic in Ethiopia.
[Plasmodium spp.]
Plasmodium Ovale
Rounded, compact trophozoites, occasionally slightly ameboid.
[Plasmodium spp.]
Plasmodium Ovale
Growing trophozoites have large chromatin mass.
[Plasmodium spp.]
Plasmodium Ovale
No. of merozoites: 6-14, average is 8.
[Plasmodium spp.]
Plasmodium Ovale
A primate malaria parasite commonly found in Southeast Asia.
[Plasmodium spp.]
Plasmodium Knowlesi
Schuffner’s dots present in all stages except early “ring forms”.
[Plasmodium spp.]
Plasmodium Ovale
It causes malaria in long-tailed macaques (Macaca fascicularis), but it may also infect humans, either naturally or artificially.
[Plasmodium spp.]
Plasmodium Knowlesi
The “fifth major human malaria parasite”.
[Plasmodium spp.]
Plasmodium Knowlesi
This is an emerging infection that was reported for the first time in humans in 1965.
[Plasmodium spp.]
Plasmodium Knowlesi
It accounts for up to 70% of malaria cases in South East Asia where it is mostly found.
[Plasmodium spp.]
Plasmodium Knowlesi
In developing trophozoites of this Plasmodium spp. band forms may appear that are similar in appearance to P. malariae.
[Plasmodium spp.]
Plasmodium Knowlesi
As the vacuole is lost during maturation of the trophozoite stage, the parasite becomes smaller and more compact.
[Plasmodium spp.]
Plasmodium Knowlesi
The pigment appears as dark grains and the red nucleus increases in size.
[Plasmodium spp.]
Plasmodium Knowlesi
Stippling appears, often referred to as ‘Sinton and Mulligan’s’ stippling.
[Plasmodium spp.]
Plasmodium Knowlesi
The typical fever in Plasmodium Knowlesi becomes?
[Plasmodium spp.]
Quotidian