Plasmodium Flashcards

1
Q

[6] Stages of Development of Plasmodium Spp.

A
  1. Ring forms
  2. Developing/ Growing Trophozoites
  3. Immature/Presegmenting Schizonts
  4. Mature Schizonts
  5. Microgametocytes
    6.Macrogametocytes
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2
Q

early trophozoites.

[stages of development of plasmodium spp]

A

Ring forms

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3
Q

As the name implies, refers to a ring like appearance of the malarial parasite following invasion into a previously healthy RBC.

[stages of development of plasmodium spp]

A

Ring forms

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4
Q

Space inside the ring is known as a vacuole.

[stages of development of plasmodium spp]

A

Ring forms

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5
Q

Remnants of the cytoplasmic circle and chromatin dot are still intact until late development.

[stages of development of plasmodium spp]

A

Developing trophozoites

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6
Q

The parasite is actively growing during this stage, the amount of RBC space invaded is significantly more than that of the ring form.

[stages of development of plasmodium spp]

A

Developing trophozoites

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7
Q

Active chromatin replication is seen.

[stages of development of plasmodium spp]

A

Immature schizonts

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8
Q

Expands and occupies more space within the RBC.

[stages of development of plasmodium spp]

A

Immature Schizonts

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9
Q

Merozoites: emergence of the fully developed stage of the asexual sprozoa trophozoite.

[stages of development of plasmodium spp]

A

Mature schizonts

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10
Q

Typical microgametocyte is roundish in shape (except P. falciparum, which is crescent-shaped)

[stages of development of plasmodium spp]

A

Microgametocytes

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11
Q

Large diffuse chromatin mass that stains pink to purple and is surrounded by a colorless to pale halo.

[stages of development of plasmodium spp]

A

Microgametocytes

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12
Q

pigment is usually visible.

[stages of development of plasmodium spp]

A

Microgametocytes

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13
Q

Round to oval (except P. falciparum, which is crescent shaped)

[stages of development of plasmodium spp]

A

Macrogametocytes

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14
Q

Pigment is also present, and its color and distribution in this morphologic form vary by individual Plasmodium species.

A

Macrogametocytes

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15
Q

Disease: malignant malaria, aestivo-autumnal, falciparum malaria, subtertian malaria, pernicious malaria, Black water fever malaria.

[Plasmodium spp.]

A

Plasmodium Falciparum

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16
Q

It is most prevalent in the tropics and subtropics.

[Plasmodium spp.]

A

Plasmodium Falciparum

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17
Q

It causes the most severe form of malaria.

[Plasmodium spp.]

A

Plasmodium Falciparum

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18
Q

It still remains almost unchallenged as the greatest killer of the human race over most parts of Africa and elsewhere in the tropics.

[Plasmodium spp.]

A

Plasmodium Falciparum

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19
Q

Maurer’s dots occasionally seen.

[Plasmodium spp.]

A

Plasmodium Falciparum

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20
Q

Pigment: BLACK, coarse and conspicuous in parasite.

[Plasmodium spp.]

A

Plasmodium Falciparum

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21
Q

Number of merozoites: 6-32, average is 20-24

[Plasmodium spp.]

A

Plasmodium Falciparum

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22
Q

Schizonts: bad prognosis

[Plasmodium spp.]

A

Plasmodium Falciparum

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23
Q

Stages found in Circulating Blood: Young, growing trophozoites (ring forms) and gametocytes.

[Plasmodium spp.]

A

Plasmodium Falciparum

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24
Q

Young rings are small, delicate, often with double chromatin dots, accole, applique.

[Plasmodium spp.]

A

Plasmodium Falciparum

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25
Q

Disease: vivax malaria or benign tertian malaria.

[Plasmodium spp.]

A

Plasmodium Vivax

26
Q

Most widespread, found in most endemic areas including some temperate zones.

[Plasmodium spp.]

A

Plasmodium Vivax

27
Q

It is more common in temperate than in tropical region.

[Plasmodium spp.]

A

Plasmodium Vivax

28
Q

It is the second common Malaria in the Philippines.

[Plasmodium spp.]

A

Plasmodium Vivax

29
Q

Ring forms occupies 1/3 diameter of RBC.

[Plasmodium spp.]

A

Plasmodium Vivax

30
Q

Schuffner’s dots present in all stages except early young forms.

[Plasmodium spp.]

A

Plasmodium Vivax

31
Q

Irregular, ameboid trophozoites, has spread out appearance.

[Plasmodium spp.]

A

Plasmodium Vivax

32
Q

Pigment: GOLDEN BROWN, inconspicuous

[Plasmodium spp.]

A

Plasmodium Vivax

33
Q

Number of merozoites: 12-24, average is 16

[Plasmodium spp.]

A

Plasmodium Vivax

34
Q

Disease: malariae or quartan malaria

[Plasmodium spp.]

A

Plasmodium Malariae

35
Q

Similar range as P. falciparum, but less common and patchy distribution.

[Plasmodium spp.]

A

Plasmodium Malariae

36
Q

Common in tropical Africa, Burma, Sri lanka, India, Malaysia and Indonesia.

[Plasmodium spp.]

A

Plasmodium Malariae

37
Q

It is occasionally seen in the Philippines.

[Plasmodium spp.]

A

Plasmodium Malariae

38
Q

Ziemann’s dots rarely seen.

[Plasmodium spp.]

A

Plasmodium Malariae

39
Q

Rounded, compact trophozoites with dense cytoplasm.

[Plasmodium spp.]

A

Plasmodium Malariae

40
Q

Band form trophozoites occasionally seen.

[Plasmodium spp.]

A

Plasmodium Malariae

41
Q

Pigment: DARK BROWN, conspicuous

[Plasmodium spp.]

A

Plasmodium Malariae
Plasmodium Ovale

42
Q

Rosette schizonts occasionally seen.

[Plasmodium spp.]

A

Plasmodium Malariae

43
Q

No. of merozoites: 6-12, average is 8.

[Plasmodium spp.]

A

Plasmodium Malariae

44
Q

Disease: ovale malaria, Benign tertian malaria.

[Plasmodium spp.]

A

Plasmodium Ovale

45
Q

It is the least common Plasmodium infecting man.

[Plasmodium spp.]

A

Plasmodium Ovale

46
Q

It occurs mostly in tropical Africa, principally on the west coast and is endemic in Ethiopia.

[Plasmodium spp.]

A

Plasmodium Ovale

47
Q

Rounded, compact trophozoites, occasionally slightly ameboid.

[Plasmodium spp.]

A

Plasmodium Ovale

48
Q

Growing trophozoites have large chromatin mass.

[Plasmodium spp.]

A

Plasmodium Ovale

49
Q

No. of merozoites: 6-14, average is 8.

[Plasmodium spp.]

A

Plasmodium Ovale

50
Q

A primate malaria parasite commonly found in Southeast Asia.

[Plasmodium spp.]

A

Plasmodium Knowlesi

51
Q

Schuffner’s dots present in all stages except early “ring forms”.

[Plasmodium spp.]

A

Plasmodium Ovale

52
Q

It causes malaria in long-tailed macaques (Macaca fascicularis), but it may also infect humans, either naturally or artificially.

[Plasmodium spp.]

A

Plasmodium Knowlesi

53
Q

The “fifth major human malaria parasite”.

[Plasmodium spp.]

A

Plasmodium Knowlesi

54
Q

This is an emerging infection that was reported for the first time in humans in 1965.

[Plasmodium spp.]

A

Plasmodium Knowlesi

55
Q

It accounts for up to 70% of malaria cases in South East Asia where it is mostly found.

[Plasmodium spp.]

A

Plasmodium Knowlesi

56
Q

In developing trophozoites of this Plasmodium spp. band forms may appear that are similar in appearance to P. malariae.

[Plasmodium spp.]

A

Plasmodium Knowlesi

57
Q

As the vacuole is lost during maturation of the trophozoite stage, the parasite becomes smaller and more compact.

[Plasmodium spp.]

A

Plasmodium Knowlesi

58
Q

The pigment appears as dark grains and the red nucleus increases in size.

[Plasmodium spp.]

A

Plasmodium Knowlesi

59
Q

Stippling appears, often referred to as ‘Sinton and Mulligan’s’ stippling.

[Plasmodium spp.]

A

Plasmodium Knowlesi

60
Q

The typical fever in Plasmodium Knowlesi becomes?

[Plasmodium spp.]

A

Quotidian