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Endocrine > pit gland histology > Flashcards

pit gland histology Flashcards

1
Q

what is superior to the pit gland?

A

diaphragma sellae and hypothalamus

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2
Q

what is inferior to the pit gland?

A

sella turcica

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3
Q

what is lateral to the pit gland?

A

cavernous sinuses

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4
Q

anteroinferior to pit gland?

A

sphenoid sinus

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5
Q

anterosuperior to pit gland?

A

optic chiasm

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6
Q

cavernous sinuses contain what structures?

A

internal carotids

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7
Q

CN __, ____,___ and ____tracts are adjacent to pit gland

A

III, IV, VI optic tract

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8
Q

what division is the anterior and the posterior pituitary derived from?

A

ectoderm

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9
Q

in the development of the pit gland, what is derived directly from the oral ectoderm prior to developing into the anterior lobe?

A

rathke’s pouch

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10
Q

the posterior lobe is directly derived from?

A

neuroectoderm

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11
Q

what are the signaling molecules for the development of the pit gland?

A

BMP-4 + FGF-8

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12
Q

Remnants of Rathke’s cleft and the craniopharyngeal duct in children

A

Craniopharyngioma

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13
Q

what does adult Craniopharyngioma develop from?

A

from mature cells in the anterior hypophysis

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14
Q

Superior hypophysial arteries supplies?

A

anterior pit

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15
Q

inferior hypophysial arteries supplies

A

posterior pit

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16
Q

a scant reticulin network in pars distalis characterizes what?

A

pituitary adenoma

17
Q

what to use if you want to ID hormone that an adenoma is producing (ie. FSH)

A

immunohistochemistry

18
Q

acidophils that secrete GH?

A

somatotropes

19
Q

acidophils that secrete prolactin

A

Mammotropes (lactotropes)

20
Q

what are the only acidophils in the pars distalis?

A

somatotropes + mammotropes

21
Q

rarely, acidophilic stem cells in a normal pit can synthesize & secrete ____ and _____

A

GH and prolactin

22
Q

basophils that secrete ACTH and β-lipotrophic hormone

A

Corticotropes

23
Q

basophils that secrete LH and FSH

A

gonadotropes

24
Q

ACTH is found where in pit?

A

mucoid wedge; can invade posterior pit

25
Q

crooke’s hyaline change is seen with what?

A

response of corticotropes to excess glucocorticoids

26
Q

collection of axons whose cell bodies reside in the supraoptic & paraventricular nucleir of the hypothalamus

A

neurohypophysis

27
Q

what are the support cells of the neurohypophysis

A

pituicytes

28
Q

paraventricular nucleus makes?

A

oxytocin

29
Q

supraventricular nucleus makes?

A

ADH

30
Q

dilatations along the length of the axons in neurohypophysis?

A

herring body

Endocrine (31 decks)

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