hypersecretion of ant pit hormones Flashcards

1
Q

what hormones are vital to human existence?

A

TSH, ACTH

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2
Q

which ant pit hormones do not have simple end organ feedback inhibitory loops?

A

GH, prolactin

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3
Q

which ant pit hormones do have simple end organ feedback inhibitory loops?

A

ACTH, TSH, FSH, LH

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4
Q

prolactin excess leads to (2)?

A

galactorrhea, hypogonadism

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5
Q

what causes hypogonadism?

A

inhibition of gnrh

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6
Q

post-menopausal woman, HA, visual field problems

A

large pit tumor

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7
Q

serum prolactin under 30?

A

stress

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8
Q

serum prolactin >300

A

pit adenoma

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9
Q

serum prolactin >100 and not preg

A

usu adenoma

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10
Q

what is the most common type of fxnal pit adenoma?

A

prolactinomas

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11
Q

is micro or macro prolactinoma more common?

A

micro

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12
Q

tx for micro prolactinoma if sx?

A

bromocriptine (DA agonist)

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13
Q

common cause of hypoprolactinemia

A

sheehan’s syndrome

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14
Q

what GH excess happens before ephiphyseal closure in peds?

A

gigantism

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15
Q

what is an insidious, chronic disease assc’d with boney and soft tissue overgrowth, middle aged ppl?

A

acromegaly

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16
Q

sx of GH excess usu present how many yrs before dx?

A

7-8 years

17
Q

what test is req’d for dx GH excess?

A

GH inhibition test with standard glu load

18
Q

tx of GH excess?

A

surgery–>transphenoidal

19
Q

are slow growing or rapidly growing tumors of the hypothalamus more common?

A

slow growing

20
Q

which hypothalamic tumor: more likely to produce dementia, food intake disturbances, endocrine dysfxn

A

slow growing

21
Q

which hypothalamic tumor: more likely to produce coma, ANS dysfxn

A

fast growing

22
Q

what to check if failure to lactate?

A

stimulation test with TRH or chlorpromazine