Physiology of Integumentary System - Repair Flashcards

1
Q

tissue is made up of:

A

cells + matrix

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2
Q

matrix

A
  • aka extracellular material

- made up of ground substance (extracellular fluid), protein, collagen fibers

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3
Q

1st step of tissue repair

A
  • blood platelets (from broken blood vessel) accumulate in area to form clot
  • secrete mesh-like substance around clot to prevent blood loss
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4
Q

2nd step of tissue repair

A
  • mast cells release histamine (chemical)
  • -> dilates blood vessels to bring increased blood + nutrients to area
  • -> initiates local inflammatory response (signals cells to remove foreign pathogens)
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5
Q

3rd step of tissue repair

A

macrophages (type of white bc) engulf and destroy disease causing pathogens

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6
Q

4th step of tissue repair

A
  • fibroblasts secrete new collagen in shape of old tissue

- -> forms framework supporting tissue matrix until new cells fully develop

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7
Q

5th step of tissue repair

A
  • remodeling: tissue matures, cells begin retaking their original functions
  • if would too deep, scar (overgrowth of fibrous connective tissue, can’t be replaced fully by og tissue) will form
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8
Q

1st degree burns

A
  • least severe
  • superficial, only damage epidermis
  • burned area becomes dry, red, painful (no blisters)
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9
Q

2nd degree burns

A
  • aka partial thickness burns
  • damage to epidermis and part of dermis
  • burned area becomes red, blistered, painful swelling (more sensory organs in dermis –> more painful)
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10
Q

3rd degree burns

A
  • aka full thickness burns
  • damage epidermis + entire dermis, sometimes part of subcutaneous tissue
  • typically, burned area has white or charred appearance
  • extremely painful
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11
Q

4th degree burns

A
  • damage all the way to tissue below hypodermis (e.g. muscle/bone)
  • nerve endings destroyed –> no sensation in area
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12
Q

skin graft

A
  • necessary if skin too damaged or burn has large surface area
  • decreases recovery time and prevents infection
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