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Clinical Chemistry > Pharmacology and TDM > Flashcards

Pharmacology and TDM Flashcards

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1
Q

Transport of Drug from the SITE to the CIRCULATION (blood)

A

Absorption

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2
Q

Delivery of the drug from the CIRCULATION to the ORGANS/TISSUES

A

Distribution

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3
Q

Release of the Drug

A

Liberation

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4
Q

Relationship between the mechanism of action of the drug or EFFECT OF THE DRUG to the BODY

A

Pharmacodynamics

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5
Q

Pharmacokinetics

A

Relationship between drug dose and drug blood level

How the body responses to the drug

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6
Q

Fastest route of Drug Administration

A

Intravenous

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7
Q

Most common route of Drug administration

A

Oral (PO)

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8
Q

Treatment for Congestive heart failure & MI

A

Digoxin

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9
Q

Tx. ventricullar arrhythmia and bentricular fibrillations

A

Lidocaine

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10
Q

Treatment for ARRHYTHMIA

A

Quinidine

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11
Q

Treatment for THYROTOXICOSIS

A

Propanolol

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12
Q

Used for GRAM (-)

A

Aminoglycosides

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13
Q

Used for GRAM (+)

A

Vancomycin

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14
Q

Psychoactive Drugs

A

Lithium

Flouxetine - PROZAC

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15
Q

Treatment of BIPOLAR DISORDERS

A

Lithium

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16
Q

Treatment of Depression

A

Tricylic antidepressants

17
Q

Treatment of obsessive-compulsive disorders (OCD)

A

Fluoxetine (Prozac)

18
Q

Immunosuppressive Drugs

A 
Cyclosporine
Tacrolimus
Rapamycin
Leflunomide
Mycophenolate
19
Q

Antiplatelet Drug

A

Aspirin/Acetyl salicylic acid

20
Q

Commonly used Analgesic and Anti-pyretic drug

A

Acetaminophine/Tylenol/Paracetamol

21
Q

Commonly used Analgesic and Anti-pyretic drug, Anti-inflammatory

A

Aspirin/Acetyl salicylic acid

22
Q

Aspirin inhibits ____________

A

Cyclooxygenase

23
Q

Analgesic: ___ hrs
Antipyretic: ___ hrs

A

Analgesic: 6 hrs
Antipyretic: 4 hrs

24
Q

Anti epileptic Drugs

A

Phenobarbital
Phenytoin
Valproic acid
Ethosuximide

25
Q

Treatment of Asthma and COPD - Bronchodilator

A

Theophylline

26
Q

Long acting Anticonvulsant

A

Phenobarbital

27
Q

Metabolite of Phenobarbital

A

Primidone

28
Q

Short-term prophylactic agent

A

Phenytoin

29
Q

Metabolite of phenytoin

A

Fosophenytoin

30
Q

Tx. Petit mal

A

Ethusuximide

31
Q

Tx. Petit mal and Grand mal

A

Valproic acid

32
Q

Painful seizure

A

Carbamazipine

33
Q

Focal/Partial seizure

A

Gabapentin

34
Q

Redman’s Syndrome

A

Vancomycin

35
Q

Causes Aplastic anemia

A

Chloramphenicol

36
Q

10x more potent than Cyclosporine

A

Tacrolimus

Clinical Chemistry (20 decks)

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