Pharmacology and TDM Flashcards
Transport of Drug from the SITE to the CIRCULATION (blood)
Absorption
Delivery of the drug from the CIRCULATION to the ORGANS/TISSUES
Distribution
Release of the Drug
Liberation
Relationship between the mechanism of action of the drug or EFFECT OF THE DRUG to the BODY
Pharmacodynamics
Pharmacokinetics
Relationship between drug dose and drug blood level
How the body responses to the drug
Fastest route of Drug Administration
Intravenous
Most common route of Drug administration
Oral (PO)
Treatment for Congestive heart failure & MI
Digoxin
Tx. ventricullar arrhythmia and bentricular fibrillations
Lidocaine
Treatment for ARRHYTHMIA
Quinidine
Treatment for THYROTOXICOSIS
Propanolol
Used for GRAM (-)
Aminoglycosides
Used for GRAM (+)
Vancomycin
Psychoactive Drugs
Lithium
Flouxetine - PROZAC
Treatment of BIPOLAR DISORDERS
Lithium
Treatment of Depression
Tricylic antidepressants
Treatment of obsessive-compulsive disorders (OCD)
Fluoxetine (Prozac)
Immunosuppressive Drugs
Cyclosporine Tacrolimus Rapamycin Leflunomide Mycophenolate
Antiplatelet Drug
Aspirin/Acetyl salicylic acid
Commonly used Analgesic and Anti-pyretic drug
Acetaminophine/Tylenol/Paracetamol
Commonly used Analgesic and Anti-pyretic drug, Anti-inflammatory
Aspirin/Acetyl salicylic acid
Aspirin inhibits ____________
Cyclooxygenase
Analgesic: ___ hrs
Antipyretic: ___ hrs
Analgesic: 6 hrs
Antipyretic: 4 hrs
Anti epileptic Drugs
Phenobarbital
Phenytoin
Valproic acid
Ethosuximide
Treatment of Asthma and COPD - Bronchodilator
Theophylline
Long acting Anticonvulsant
Phenobarbital
Metabolite of Phenobarbital
Primidone
Short-term prophylactic agent
Phenytoin
Metabolite of phenytoin
Fosophenytoin
Tx. Petit mal
Ethusuximide
Tx. Petit mal and Grand mal
Valproic acid
Painful seizure
Carbamazipine
Focal/Partial seizure
Gabapentin
Redman’s Syndrome
Vancomycin
Causes Aplastic anemia
Chloramphenicol
10x more potent than Cyclosporine
Tacrolimus