Pharmaceutics / Drug formulation Flashcards
1
Q
What 4 things does ideal drug delivery systems need to achieve?
A
Improved bioavailability
enhanced therapeutic profile of drug
patient adherence
convince and safety to patient
2
Q
How can you enhance solubility?
A
pH adjust
solid dispersion, particle size reduction, salts, co-solvents, micelles, emulsion, lipids systems
3
Q
How to enhance permeability
A
efflux inhibitors tight junction openings metabolic inhibitors motility modifiers pro drugs
