PHARMA anti Mycobacterial Flashcards
0
Q
High level resistance of inh
A
Deletion of kat g gene
1
Q
INH moa
A
Inhibits mycolic acid synthesis
2
Q
Low level resistance of inh
A
Changed inhA gene
3
Q
AhpC virulence gene and kasA mutation cause resistance in?
A
Isoniazid
4
Q
Drugs that cause sle like symptoms
A
ISONIAZID
Procainamide
Hydralazine
5
Q
Inh adr
A
Peripheral neuritis so give pyridoxine
Inc level of phenytoin and carbamazepine
6
Q
Rifampin moa
A
Inhibits DNA-dependent RNA polymerase
7
Q
Causes harmless red orange metabolites in secretions
A
Rifampin
8
Q
Resistance emerges rapidly if used alone
A
Rifampin
9
Q
Inhibits arabinosyltransferase, blocks formation of ARABINOGLYCAN
A
Ethambutol
10
Q
Dose dependent retrobulbar neuritis
A
Ethambutol
