PH: Cancer Prevention

Question 1

How can you identify those at highest risk of developing breast cancer?

Answer 1

Family history, reproductive/hormonal factors, mammographic density, physical exercise, reproduction (breast feeding), post-menopausal syndrome.

Question 2

How can aspirin affect the likelihood of GI cancer?

Answer 2

Can reduce the risk if used for a minimum of 5 years at a dose of 75-325mg/day

Question 3

What drugs may be used in the prevention of breast cancer?

Answer 3

SERMs (tamoxifen and raloxifene), aromatase inhiitors (anastrozole, letrozole, exemestane) as well as metformin and bisphosphonates

Question 4

What drugs may be used in the prevention of prostate cancer?

Answer 4

reductase inhibitors (finasteride, dutasteride) reduce low-grade tumours, but may increase size of high-grade tumours. Vitamin E and selenium INCREASE the risk of prostate cancer.

Question 5

What drugs may increase the risk of developing lung cancer?

Answer 5

Beta carotene

Question 6

Which drugs may increase the risk of developing prostate cancer?

Answer 6

Vitamin E and selenium