Adverse Drug Reactions

Question 1

What is a Type A adverse drug reaction?

Answer 1

Augmented reaction - there is an exaggeration of a drug’s normal action when given at a usual therapeutic dose

Question 2

Which drugs are more likely to present with a Type A adverse drug reaction?

Answer 2

antiplatelet, diuretics, NSAIDs and anticoagulants

Question 3

What is a Type B adverse drug reaction?

Answer 3

Bizarre reaction - novel responses that are not expected from known pharmacological response

Question 4

What is a Type C adverse drug reaction?

Answer 4

Continuing reaction - reactions persistent for a relatively long time after discontinuation of the medication. Examples include: bisphosphonates (osteonecrosis of the jaw), corticosteroids (osteoporosis)

Question 5

What is a Type D adverse drug reaction?

Answer 5

Delayed reaction - reactions that become apparent some time after use of a medication. Examples include: carbimazole (agranulocytosis), typical antipsychotics (tardive dyskinesia), chemotherapy (infertility)

Question 6

What is a Type E adverse drug reaction?

Answer 6

End of use - reactions associated with withdrawal of medications. Examples include: benzodiazepines, corticosteroids and opiates.

Question 7

What is a Type F adverse drug reaction?

Answer 7

Failure reactions

Question 8

What is a Type G adverse drug reaction?

Answer 8

Genetic reactions

Question 9

What is a Type I adverse drug reaction?

Answer 9

Idiosyncratic reactions