Peripheral artery disease (PAD) Flashcards
Peripheral artery disease (PAD)
- involves thickening of artery walls
* results in a progressive narrowing of the arteries of the upper and lower extremities
atherosclerosis
- a gradual thickening/hardening of the intima (the innermost layer of the arterial wall) and media (middle layer of the arterial wall).
- results from the deposit of cholesterol and lipids within the vessel walls and leads to progressive narrowing of the artery.
intermittent claudication
- cramplike pains in the calves caused by poor circulation of the blood to the leg muscles.
- pain you feel when your leg muscles don’t get enough blood while you exercise
Critical limb ischemia (CLI)
a severe blockage in the arteries of the lower extremities, which markedly reduces blood-flow
Note: Ischemia is a condition in which the blood flow (and thus oxygen) is restricted or reduced in a part of the body.
Raynaud’s phenomenon
aproblem that causes decreased blood flow to the fingers
Aneurysm
Loss of elasticity of media layer of arterial wall causing thinning and bulging of aortic wall
Aortic Dissection
Tear in intimal layer of arterial wall allows bleeding into the media layer and a pool or bulge of blood results
Leads to compression & occlusion of surrounding vessels and/or rupture
Acute Arterial Ischemia
- a sudden interruption in the arterial blood supply to a tissue, organ, or extremity
- if left untreated, can result in tissue death.
- caused by embolism, thrombosis of a pre-existing atherosclerotic artery, or trauma
- sudden loss of limb perfusion for up to 2 weeks after an inciting event
thrombus
a blood clot that forms in a vessel and remains there
Arterial Leg Ulcers
also referred to as ischemic ulcers, are caused by poor perfusion (delivery of nutrient-rich blood) to the lower extremities.
Typically toes, heels, bony prominences of the foot
“Punched out” well demarcated edges
Complication as a result in changes in circulation
Phlebitis
imflamation of vein
Venous thrombosis
blockage of a vein caused by a thrombus (blood clot).
Deep vein thrombosis (DVT, also called venous thrombosis) is a blood clot that develops in a vein deep in the body
involves the formation of a thrombus (blood clot) in association with inflammation of the vein.
• represents the spectrum of pathology from deep/superficial vein thrombosis (DVT) to pulmonary embolism (PE),
Varicose veins
- twisting veins caused by increased pressure.
- veins become enlarged, dilated, and overfilled with blood
- superficial veins that have dilated due to a weakness in the veins walls or from an injury to the vein.
Chronic venous insufficiency
occurs when your leg veins don’t allow blood to flow back up to your heart. When valves don’t work well, blood can also flow backwards. This can cause blood to collect (pool) in your legs.
• can lead to venous leg ulcers
venous leg ulcers
- also know as stasis ulcer
- From chronic venous insufficiency
- Often accompanied by stasis dermatitis & pruritus (itchy skin/skin irritatoin)
- Partial thickness
- Painful
- Extensive drainage
- Can lead to infection, cellulitis
- normally on ankle or between ankle/knee
Virchow’s Triad
1) Hypercoagulability of blood
2) Damage to endothelium
3) Venous Stasis
Note: Hypercoagulability can be defined as the tendency to have thrombosis as a result of certain inherited and/or acquired molecular defects
Venous stasis
values or leg muscles aren’t working properly to move the blood back to heart.
• Chronic condition that causes imflammation ulcers and itchy skin to lower legs
• As fluid/pressure builds up, some of the fluid leaks out
• occurs when the valves are dysfunctional or the muscles of the extremities are inactive.
Venus statis
values or leg muscles aren’t working properly to move the blood back to heart.
• Chronic condition that causes imflammation ulcers and itchy skin to lower legs
• As fluid/pressure builds up, some of the fluid leaks out
Superficial Vein Thrombosis
is inflammation and clotting in a superficial vein,
DVT – Deep vein thrombosis
is a medical condition that occurs when a blood clot forms in a deep vein.
PE - Pulmonary Embolism
- a blood clot that develops in a blood vessel in the body (often in the leg). It then travels to a lung artery where it suddenly blocks blood flow.
- an embolus that lodges in the pulmonary circulation.
Anticoagulants
commonly called blood thinners –but they don’t thin the blood”
used to treat DVT or PE
preventing the clot from becoming larger while the body slowly reabsorbs it,
reducing the risk of further clots developing.
Thrombus
blood clot
embolus
anything that moves through the blood vessels until it reaches a vessel that is too small to let it pass